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The development and maintenance of an organism is orchestrated by a set of chemical reactions that switch parts of the genome off and on at strategic times and locations. Epigenetics is the study of these reactions and the factors that influence them.

In biology, and specifically genetics, epigenetics is the study of changes in gene expression caused by mechanisms other than changes in the underlying DNA sequence – hence the name epi- (Greek: επί- over, above, outer) -genetics. Examples of such changes might be DNA methylation or histone deacetylation, both of which serve to suppress gene expression without altering the sequence of the silenced genes.

These changes may remain through cell divisions for the remainder of the cell's life and may also last for multiple generations. However, there is no change in the underlying DNA sequence of the organism; instead, non-genetic factors cause the organism's genes to behave (or "express themselves") differently.

One example of epigenetic changes in eukaryotic biology is the process of cellular differentiation. During morphogenesis, totipotent stem cells become the various pluripotent cell lines of the embryo which in turn become fully differentiated cells. In other words, a single fertilized egg cell – the zygote – changes into the many cell types including neurons, muscle cells, epithelium, blood vessels etc. as it continues to divide. It does so by activating some genes while inhibiting others.

EPIGENETICS & THE ENVIRONMENT
The genome dynamically responds to the environment. Stress, diet, behavior, toxins and other factors activate chemical switches that regulate gene expression.

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Epigenetics Market by Product (Kit, Enzymes, Reagent, NGS, Mass Spectrometer, PCR, Bioinformatics), Application (Oncology, Cardiology, Immunology), Technology (DNA Methylation, Histone Modification), End User (Academic, CRO) - Global Forecast to 2022 [Report Updated: 12-10-2017]

“The Global Epigenetics Market Is Projected to Register a CAGR of 13.5% During the Forecast Period (2017–2022).”The global epigenetics market is projected to reach USD 1,605.7 million by 2022 from USD 854.0 million in 2017, at a CAGR of 13.5% during the forecast period. The decreasing sequencing costs and time, increasing research activities, favorable funding scenario for epigenetics resear...Read More >>>

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Cancer Tumor Profiling Market by Technology [Next-generation Sequencing (NGS), Polymerase Chain Reaction (PCR), Immunohistochemistry (IHC), In Situ Hybridization (ISH), (Fluorescence In Situ Hybridization (FISH) and Chromogenic in Situ Hybridization (CISH)), Microarray, and Others], Technique (Genomics, Proteomics, Epigenetics, and Metabolomics), and Application (Personalized Medicine, Diagnostics [Report Updated: 01-08-2017]

Cancer/tumor profiling uses several molecular biology techniques, such as microarray, polymerase chain reaction (PCR), and in situ hybridization (ISH), to provide specific information about genetic and molecular makeup of tumor. It can detect the presence or absence of distinct disease-associated targets that guide medical practitioners in deciding the appropriate course of treatment for patients....Read More >>>

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Epigenetics Market by Product [Enzymes (DNA Ligases, DNA Polymerases, Other DNA-modifying Enzymes), Kits & Assays (Bisulfite Conversion Kits, Chip-Seq Kits, Deep Sequencing Kits, Methyltransferase Assays, Histone Assays, Immunoprecipitation Kits), Instruments (Mass Spectrometers, Next-generation Sequencers, qPCRs, and Sonicators), and Reagents (Antibodies, Buffers, Histones, Magnetic Beads, Primer [Report Updated: 30-05-2017]

CHAPTER 1 INTRODUCTION1.1. REPORT DESCRIPTION1.2. KEY BENEFITS1.3. KEY MARKET SEGMENTS1.4. RESEARCH METHODOLOGY1.4.1. Secondary research1.4.2. Primary research1.4.3. Analyst tools & modelsCHAPTER 2 EXECUTIVE SUMMARY2.1. CXO PERSPECTIVECHAPTER 3 MARKET OVERVIEW3.1. MARKET DEFINITION AND SCOPE3.2. KEY FINDINGS3.2.1. Top investment pockets3.2.2. Top winning strategies3.3. TOP PLAYER POSITIONING3.4. P...Read More >>>

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NGS-based RNA-seq Market by Products & Services (Sample Preparation, Consumables, Bioinformatics), Technology (SBS, SMRT), Application (De novo, Transcriptome Epigenetics, Small RNA), End User (Research Centers, BioPharma Companies) - Global Forecast to 2022 [Report Updated: 26-05-2017]

The global NGS-based RNA-seq market is projected to reach USD 2.65 billion by 2022 from USD 1.05 billion in 2017, at a CAGR of 20.2%. Factors such as the advantages of RNA-seq over microarray technology, technological advancements in RNA-seq products, increasing number of RNA-seq grants, increasing number of research activities, and rapid growth in precision medicine are driving the growth of the ...Read More >>>

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High-Resolution Melting Analysis Market by Product (Supermix Reagent, RT PCR Instrument, Software), Application (SNP Genotyping, Mutation Discovery, Epigenetics), Enduser (Research Laboratories, Hospital, Diagnostic Center) - Global Forecast to 2021 [Report Updated: 25-04-2017]

The global high-resolution melting analysis market is expected to reach USD 302.1 million by 2021 from USD 259.4 million in 2016, at a CAGR of 3.1% during the forecast period of 2016 to 2021. On the basis of product & service, the high-resolution melting analysis market is segmented into instruments, reagents & consumables, and software & services. The reagents and consumables segment dominated th...Read More >>>

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