Follow RSS for latest reports on this topicAPC (Adenomatous Polyposis Coli) - Market Research and Reports

APC stands for adenomatous polyposis coli, a form of colorectal cancer and is a tumour suppressor. When APC it mutated, it can cause this particular type of colorectal cancer. When not present in its correct form, APC is correlated with increased risk of chromosomal disjunction because APC is located on kinetochores. This can cause patients to become susceptible to multiple polyps in the colon.

The disease caused by APC mutations is due to the fact that APC regulates myc via B-cat,a beta-catenin protein.

But the actions of APC are not just limited to the gut. Research suggests that APC is involved in the assembly of receptors in the nervous system that respond to nicotinic acetylcholine neurotransmitter.

 

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