$7495 | Single User
$14990 | Site License
$22485 | Global License

HIV -- KOL Insight and Consensus Outlook Modules
[Lowest Price Guaranteed: $7,495]

Published by FirstWord Pharma: 24 Feb 2013 | 100 | In Stock
Related Topics: Gold , Healthcare , Home , Immunology , Infectious Disease , Investment , Medical , Products , Services



What do frontline clinicians really think about current HIV treatment pathways and what are the most pressing unmet needs that industry can respond to?

What’s driving long term growth in HIV?

The market for HIV therapies has been growing fast–a 5 year CAGR (2007-2012) of 12.0%–but sustaining growth will be a challenge. The HIV sector is mature with many tried and tested treatment options, so what has underpinned growth to date and how can companies drive market expansion in the future?

The patient population is key

Current HIV therapies are effective in suppressing HIV and are successfully increasing patients’ life expectancy. However, they are not curative and must be taken for the lifetime of the patient. This means the market for HIV therapies will be sustained from the long-term maintenance of the current patient base whose numbers will swell as new cases are diagnosed.

Good times, bad times?

Valued at US billion in 2012, and with a 5-year CAGR (2007-2012) of 12.0 percent, the HIV sector is dominated by seven blockbuster drugs: Gilead’s Atripla and Truvada; Bristol Myers-Squibb’s Reyataz; Merck & Co.’s Isentress; Janssen Therapeutics’ Prezista; ViiV Healthcare’s Epzicom/Kivexa; and AbbVie’s Kaletra. With few payer restrictions on prescribing HIV therapies, no prospect of a cure or vaccine in the near future and limited uptake of generics to date, the sector is forecast to maintain stable returns until the end of the decade. However, driving high growth will be a challenge, and new products must show significant clinical and patient benefits if they are to succeed in a market already provided with established therapy options.

Game changers in the pipeline?

Medical adherence, improved efficacy and reducing toxicity are major challenges and there are a number of promising candidates in late trials–but how will they fare? Will ViiV Healthcare price Trii, its first single-tablet complete regimen, competitively? Tobira Therapeutics cenicriviroc has novel anti-inflammatory effects, but what are the regulatory hurdles it will have to overcome? And Gilead’s tenofovir alafenamide could address safety concerns associated with tenofovir; can it limit competition from generic alternatives?

Meeting the challenge of unmet need

Many of the challenges faced by clinicians are not related to efficacy, but include poor adherence to treatment, often exacerbated by societal and mental health issues, the stigma associated with diagnostic testing and low levels of early diagnosis. There are, however, opportunities for industry to improve patient outcomes. For example:

  • Poor adherence to prescribing programmes is a major issue in the management of HIV. Long acting injectable formulations and single dose combination therapies may help tackle this problem and in turn reduce transmission rates.

  • Under diagnosis or late diagnosis often leads to patients presenting with advanced infection. This is a notoriously difficult area to influence, but could home self diagnosis be part of the answer? Only OraQuick’s In-Home HIV test is approved in the US and there are none in Europe.

  • As first-line anti-retroviral regimens have similar efficacy, the choice of therapies is determined by the type and likelihood of long term adverse effects such a renal function impairment and cardiovascular disease. New complete combination regimens may address some of these safety concerns, but products with reduced side-effect profiles are both a development challenge and market opportunity.

  • A complete ongoing analysis of current trends, forecasts and landscape modifiers

    Harnessing the real world insights from leading US/European KOLs and research analysts, this study critically examines the HIV sector to expose the real potential. If you need instant access to an accurate, unbiased, qualitative review of the latest treatment trends along with a five-year quantitative HIV market forecast and insights as to the how HIV treatment will develop, look no further than FirstWord’s Therapy Trends: HIV. This insightful FirstWord research is provided in two comprehensive modules:

  • The KOL Insight: HIV module provides a complete review underpinned by exclusive in-depth interviews with leading KOLs from the US and Europe

  • The Consensus Outlook: HIV data analysis module provides annual historical and forecast product-level sales data based on leading equity analysts’ projections. Key findings are given in a written analysis to support the visual data analyses provided in charts and tables.

  • KOL Insight

    KOL Insight Report

  • A qualitative analysis of the current and predicted treatment trends, clinical products and commercial drivers and resistors in the global HIV market, informed by in-depth expert views of the leading clinicians

  • Compare the market’s key players, marketed products, late-stage pipeline drugs, current and future product positioning, in the context of HIV market trends.

  • Event Bulletins

  • Benefit from the latest KOL views about significant future event-driven changes in HIV treatment trends.

  • Consensus Outlook

    Consensus Report

  • An in-depth 5-year Consensus Outlook report of predicted quantitative changes in key HIV market forecast parameters drawn from 13 leading analyst and brokerage companies

  • Chart HIV market size, product sales, market share by company, competitive status and detailed forecasts

  • Interactive Analytics File

  • Use the interactive Excel market analytics module of detailed market and product sales data from 2007 to 2017 to drill down and assess key company, market and product trends

  • Scope

    KOL Insight

    Therapy Trends KOL Insight: HIV analyses the current and predicted key issues, current products and late-stage pipeline products. The report gives you qualitative, inside information from exclusive and detailed FirstWord interviews with 12 of the foremost key opinion leaders (KOLs) active in HIV treatment clinics in the US and Europe through the following:

  • KOL Insight Report—an in-depth analytical report on HIV treatment trends

  • Full report updates—delivered to you after each and every significant HIV market event

  • Event Bulletins—highlighting the latest KOL views in response to each event

  • Key Report Features and Benefits

  • Critical insights on products and market developments from leading US and European clinicians

  • Complete coverage of all therapeutic approaches

  • Assessment of current leading HIV products by class

  • Analysis of late-stage pipeline HIV therapies by class

  • Competitive evaluation of leading players

  • Current opinion and trends on the diagnosis and treatment of HIV

  • KOL predicted treatment trends and market leaders

  • Ongoing clinical and market updates

  • All current therapeutic approaches covered

  • Nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs)

  • •Non-nucleoside reverse transcriptase inhibitors (NNRTIs)

  • Integrase inhibitor

  • Protease inhibitors

  • CCR5 inhibitor

  • Expert Opinion for Real World Insights

    The data and analysis in the report is enriched through the specific insights and opinions of leading clinicians working in HIV in the US and Europe. Their views on specific drugs and treatment pathways provide a unique front line perspective from those working in a clinical setting. The results of these detailed and extensive interviews are incorporated throughout the text so they can be read in the context of the issue or product being discussed.

    Key Quotes from the Report

    “We know that patients who are on therapy do better if they are taking one pill a day, as a combination pill, there is no question about that. We need the best possible fixed dose single combination pill.”

    “Every patient who takes the drugs will be able to suppress the virus, so the question is not the potency of the combination, the question is the toxicity in the long-term. What about the kidneys? I mean everybody is taking tenofovir. We see the renal problems after years. We have an aging (HIV) population and we have to be prepared for the long run and I don't think we really are.”

    “There are a lot of expectations with Trii. I cannot think of another drug where the expectations were as high. Trii could be a good option for many different patients, and you don’t have to worry about the renal issues. It's highly potent, very well tolerated, it doesn't have a signature toxicity. I see a bright future for Trii.”

    “Current NNRTIs have a low barrier for resistance and a significant amount of patients are going to fail eventually with K103N [mutation]. Having an NNRTI that is able to overcome mutations is important.”

    “My personal view is that it will have a very small impact. We know PrEP with Truvada works. The major problem is cost. You need to give the medicines to plenty of uninfected subjects to prevent a few cases of HIV.”

    Consensus Outlook

    Use this detailed report and powerful interactive Excel spread sheet to compare and contrast companies and products now and in the future. Therapy Trends Consensus Outlook: HIV includes the following comprehensive resources:

  • An in-depth forecast report based on consensus figures from 13 leading analysts. Rich in tables and charts, the report maps the impact of future events to predict product and company performance

  • An interactive forecast data analysis spreadsheet comparing critical market parameters including market size, product sales, market shares and competitive status over the period 2007 to 2017

  • Timely event-driven market forecast report and data analysis updates over 12 months.

  • Report features:

  • Historical HIV sales from 2007–2012

  • Forecast HIV sales from 2013-2017

  • Key competitors and drug developers

  • Current and late-stage pipeline drugs

  • Future event mapping to forecast data points

  • Use Consensus Outlook to:

  • Chart predicted market growth and product sales

  • Map your own market parameters

  • Tailor your strategic and investment focus

  • Assess your current and future sales resources

  • Set proactive launches and branding strategies

  • Analysts compared

  • Barclays Capital

  • Credit Suisse

  • Deutsche Bank

  • Goldman & Sachs

  • International Strategy & Investment

  • Jefferies

  • JP Morgan

  • Merrill Lynch

  • Morgan & Stanley

  • Societe Generale

  • Stifel Nicolaus

  • UBS

  • Wells Fargo

  • Content Highlights and Products Covered:

  • FirstWord Analysis Highlights

  • Research Methodology

  • HIV Marketplace

  • Key HIV Developers

  • HIV Class Dynamics

  • Atripla (tenofovir/emtricitabine/efavirenz; Gilead Sciences) forecast

  • Complera/Eviplera (tenofovir/emtricitabine/rilpivirine; Gilead Sciences) forecast

  • Reyataz (atazanavir; Bristol-Myers Squibb) forecast

  • Prezista (darunavir; Janssen Therapeutics) forecast

  • Kaletra (lopinavir/ritonavir; AbbVie) forecast

  • Isentress (raltegravir; Merck & Co) forecast

  • Stribild (tenofovir/emtricitabine/elvitegravir/cobicistat; Gilead Sciences) forecast

  • Tivicay (dolutegravir; ViiV Healthcare) forecast

  • Selzentry/Celsentri (maraviroc; ViiV Healthcare) forecast

  • Norvir (ritonavir, Abbvie) forecast

  • Sustiva (efavirenz; Bristol-Myers Squibb) forecast

  • Tenofovir (alafenamide/emtricitabine/cobicistat/elvitegravir; Gilead Sciences) forecast

  • Truvada (tenofovir/emtricitabine; Gilead Sciences) forecast

  • Viread (tenofovir; Gilead Sciences) forecast

  • Edurant (rilpivirine ; Janssen Therapeutics) forecast

  • Intelence (etravirine; Janssen Therapeutics) forecast

  • Prezista (darunavir; Janssen Therapeutics) forecast

  • Stocrin (efavirenz; Merck & Co) forecast

  • Combivir(lamivudine/zidovudine; ViiV Healthcare) forecast

  • Epzicom/Kivexa (abacavir/lamivudine; ViiV Healthcare) forecast

  • Lexiva/Telzir (fosamprenavir ;ViiV Healthcare) forecast

  • Tivicay/(Trii) (dolutegravir (+abacavir/lamivudine; ViiV Healthcare) forecast

  • Trizivir (abacavir/lamivudine/zidovudine; ViiV Healthcare) forecast

  • KOL, Analysts, Products and Companies

    At a glance listings of those who contributed and the rich and varied sources used to produce this major analysis of the HIV market and its prospects.

    Key Opinion Leaders

  • Dr Jay Dobkin MD, Associate Attending Physician, Columbia-Presbyterian Hospital, New York, USA

  • Dr Monica Gandhi MD, Associate Professor of Clinical Medicine, UCSF, California, USA

  • Dr Edwin DeJesus MD, HIV Specialist and Medical Director, Orlando Immunology Center, Florida, USA

  • Dr. Joel Gallant MD, Associate Medical Director of Specialty Services, Southwest CARE Center - Santa Fe, New Mexico, USA

  • Dr Richard Haubrich MD, Professor of Medicine in the Department of Medicine, Division of Infectious Diseases, UCSD, California, USA

  • Dr Bruce Agins MD, Medical Director New York State Department of Health AIDS Institute, New York, USA

  • Dr Barry Peters, Consultant Physician, Guy's and St Thomas Hospital, London‏, England

  • Dr Christian Hoffmann MD, Infektionsmedizinisches Centrum Hamburg (ICH), Hamburg Germany

  • Dr Magnus Gisslén, HIV Unit, Department of Infectious Diseases, Sahlgrenska University Hospital, Gothenburg, Sweden

  • Dr Jean-Michel Molina, Saint-Louis Hospital and University of Paris, France

  • Dr Pere Domingo Pedrol, Hospital Santa Creu I Sant Pau, Barcelona, Spain

  • Dr José Arribas, Hospital La Paz, Madrid, Spain

  • Analysts

  • Barclays Capital

  • Credit Suisse

  • Deutsche Bank

  • Goldman & Sachs

  • International Strategy & Investment

  • Jefferies

  • JP Morgan

  • Merrill Lynch

  • Morgan & Stanley

  • Societe Generale

  • Stifel Nicolaus

  • UBS

  • Wells Fargo

  • Products & Companies Covered

  • Truvada (tenofovir/emtricitabine); Gilead

  • Epzicom/Kivexa (abacavir/lamivudine); ViiV Healthcare

  • Atripla (tenofovir/emtricitabine/efavirenz); Gilead

  • Complera/Eviplera (tenofovir/emtricitabine/rilpivirine); Gilead

  • Reyataz (atazanavir); Bristol-Myers Squibb

  • Prezista (darunavir); Janssen Therapeutics

  • Kaletra (lopinavir/ritonavir); AbbVie

  • Isentress (raltegravir); Merck & Co.

  • Stribild (tenofovir/emtricitabine/elvitegravir/cobicistat); Gilead

  • Tivicay (dolutegravir); ViiV Healthcare

  • Selzentry/Celsentri (maraviroc); ViiV Healthcare

  • Ongoing Benefits

    Updated Continually

    This report is continually updated in response to market developments stay in touch with the latest developments and thinking and maximise the value of this report

    The world of pharma is ever changing and executives must always be up-to-date with the latest developments that could affect their own products, position and research. That is why FirstWord’s guarantee to keep Therapy Trends updated offers real commercial advantage. Consider the benefits:

  • Content will be fully updated in response to market developments such as new product approvals or pivotal research results for 12 months from the date of purchase

  • Such updates are incorporated throughout the KOL reports ensuring the change is reflected in every aspect of the report

  • There is no limit and all relevant events will result in an update

  • You’ll receive these updated directly, within days of each event’s occurrence

  • All updates are included in the price.

  • Whatever happens in the market you’ll always be able to assess the impact with FirstWord Therapy Trends

    Unrivalled Sources Ensure Complete Coverage

    Our unique disease selection matrix pinpoints those disease sectors of the highest commercial potential, and draws information from multiple novel and expert sources, including:

  • Exclusive views from leading global experts

  • Comprehensive consensus research

  • Live meeting dispatches and critical industry data

  • Data from over 125 medical conferences attended by FirstWord researchers each year

  • Online opinions from 535,000 vetted physicians

  • Over 2,000 peer-reviewed medical journals

  • Over 450 pharmaceutical news sources

  • Table of Contents
    for HIV -- KOL Insight and Consensus Outlook Modules

    • Contents Consensus Outlook


      2.FirstWord Analysis Highlights

      3.Research Methodology

      4.HIV Marketplace

      5.Key HIV Developers

      6.HIV Class Dynamics

      7.Single-tablet complete regimens

      7.1.Atripla (tenofovir/emtricitabine/efavirenz; Gilead/Bristol-Myers Squibb) forecast

      7.2.Complera/Eviplera (tenofovir/emtricitabine/rilpivirine; Gilead) forecast

      7.3.Stribild (tenofovir/emtricitabine/elvitegravir/cobicistat; Gilead) forecast

      7.4.Tenofovir alafenamide fumarate (TAF)/emtricitabine/cobicistat/elvitegravir; Gilead forecast

      7.5.Trii (dolutegravir/abacavir/lamivudine; ViiV Healthcare) forecast

      8.Nucleoside reverse transcriptase inhibitors

      8.1.Truvada (tenofovir/emtricitabine; Gilead) forecast

      8.2.Epzicom/Kivexa (abacavir/lamivudine; ViiV Healthcare) forecast

      8.3.Viread (tenofovir; Gilead) forecast

      9.Protease inhibitors

      9.1.Prezista (darunavir; Janssen Therapeutics) forecast

      9.2.Reyataz (atazanavir; Bristol-Myers Squibb) forecast

      9.3.Kaletra (lopinavir/ritonavir; AbbVie) forecast

      9.4.Norvir (ritonavir; AbbVie) forecast

      10.Integrase strand transfer inhibitors

      10.1.Isentress (raltegravir; Merck & Co.) forecast

      10.2.Tivicay (dolutegravir; ViiV Healthcare) forecast

      11.Non-nucleoside reverse transcriptase inhibitors

      11.1.Intelence (etravirine; Janssen Therapeutics) forecast

      11.2.Sustiva/Stocrin (efavirenz; Bristol-Myers Squibb/Merck & Co.) forecast

      12.Entry Inhibitors

      12.1.Selzentry/Celsentri (maraviroc; ViiV Healthcare) forecast


      Contents KOL Insight

      1.Executive summary



      4.Current HIV market

      4.1.HIV treatments

      4.2.HIV treatment landscape

      4.2.1.HIV market definition

      4.2.2.Current market overview by class

      4.2.3.Current market overview by brand

      4.3Reimbursement/formulary coverage of HIV drugs



      5.Current marketed therapies

      5.1.NRTI “backbone” drugs

      5.1.1.Truvada (tenofovir/emtricitabine); Gilead

      5.1.2.Epzicom/Kivexa (abacavir/lamivudine); ViiV Healthcare

      5.2.NNRTI-based regimens

      5.2.1.Atripla (tenofovir/emtricitabine/efavirenz); Gilead

      5.2.2.Complera/Eviplera (tenofovir/emtricitabine/rilpivirine); Gilead

      5.3.Protease inhibitor-based regimens

      5.3.1.Reyataz (atazanavir); Bristol-Myers Squibb

      5.3.2.Prezista (darunavir); Janssen Therapeutics

      5.3.3.Kaletra (lopinavir/ritonavir); AbbVie

      5.4.Integrase inhibitor-based regimens

      5.4.1.Isentress (raltegravir); Merck & Co.

      5.4.2.Stribild (tenofovir/emtricitabine/elvitegravir/cobicistat); Gilead

      5.4.3.Tivicay (dolutegravir); ViiV Healthcare

      5.5.CCR5 inhibitors

      5.5.1.Selzentry/Celsentri (maraviroc); ViiV Healthcare

      6.Pipeline HIV therapies

      6.1.Integrase inhibitor-based regimens

      6.1.1.Tenofovir alafenamide/emtricitabine/cobicistat/elvitegravir; Gilead

      6.1.2.Trii (dolutegravir/abacavir/lamivudine); ViiV Healthcare

      6.1.3.GSK1265744; ViiV Healthcare

      6.2.Protease inhibitor-based regimens

      6.2.1.Tenofovir alafenamide/emtricitabine/cobicistat/darunavir; Gilead

      6.3.NNRTI-based regimens

      6.3.1.Doravirine; Merck & Co.

      6.4.CCR5 antagonists

      6.4.1.Cenicriviroc; Tobira Therapeutics

      6.5.Treatment focus

      6.5.1.Unmet needs

      6.5.2.Unmet need one: Developing an HIV cure

      6.5.3.Unmet need two: Improve patient drug adherence

      6.5.4.Unmet need three: Identify interventions to reduce HIV infections

      6.5.5.Unmet need four: Reducing long term toxicities of ART

      6.5.6.Unmet need five: Improve HIV diagnosis

      Current HIV treatment algorithm

      6.6.HIV treatment guidelines

      6.6.1.Cost of ART drugs


      6.7.Future treatment algorithm


      7.1.KOL biographies

      7.1.1.US KOLs

      7.1.2.European KOLs

    Additional Details


    FirstWord Pharma

    Publisher Information


    100 |

    Number of Pages


    Report Format


    FirstWord Pharma Reports

    Related Reports

    TitleDate PublishedPrice fromMore Details
    Malignant Melanoma: KOL Insight
    IntroductionMalignant Melanoma: PD-1 inhibitors revolutionise treatment is a comprehensive report wi...
    17 Oct 2014 by FirstWord Pharma USD $7,900 More Info
    KOL Insight: Multiple Sclerosis
    IntroductionRecent launches of oral therapies have brought clinical advantages and clear patient ben...
    06 Oct 2014 by FirstWord Pharma USD $7,900 More Info
    Chronic Lymphocytic Leukaemia: KOL Insight
    IntroductionChronic lymphocytic leukaemia (CLL) is the most common of the leukaemias, but until rece...
    27 May 2014 by FirstWord Pharma USD $7,900 More Info
    Diabetes -- KOL Insight and Consensus Outlook Modules
    IntroductionThe medium term: battle lines are drawnThe fundamental drivers of the global diabetes ma...
    01 May 2014 by FirstWord Pharma USD $7,900 More Info
    Breast Cancer: New targeted therapies transform treatment - KOL Insight
    IntroductionThe introduction of targeted therapies revolutionised the breast cancer market, widening...
    10 Feb 2014 by FirstWord Pharma USD $7,900 More Info
    Chronic Obstructive Pulmonary Disorder (COPD) - KOL Insight and Consensus Outlook
    IntroductionThe prevalence of Chronic Obstructive Pulmonary Disorder (COPD) is increasing globally, ...
    20 Jan 2014 by FirstWord Pharma USD $7,495 More Info
    Multiple Sclerosis: KOL Insight
    IntroductionThe multiple sclerosis treatment landscape has undergone dramatic changes over the past ...
    01 Dec 2013 by FirstWord Pharma USD $7,900 More Info
    KOL Insight: Prostate Cancer: Competition intensifies in race to the top
    IntroductionThe Prostate Cancer market has seen a number of progressive changes in recent years. The...
    01 Nov 2013 by FirstWord Pharma USD $7,900 More Info
    Colorectal Cancer -- KOL Insight Module
    IntroductionThe global market for colorectal cancer (CRC) drugs is undergoing a fundamental shift du...
    01 Oct 2013 by FirstWord Pharma USD $7,900 More Info
    Multiple Sclerosis -- KOL Insight and Consensus Outlook Modules
    IntroductionThe multiple sclerosis treatment landscape has undergone dramatic changes over the past ...
    12 Mar 2013 by FirstWord Pharma USD $7,495 More Info

    This report is published by FirstWord Pharma

    Download Free Report Summary PDF

    HIV -- KOL Insight and Consensus Outlook Modules | Download PDF Summary

    Download our FREE report summary PDF. It contains all the information on these web pages, plus a Proforma Invoice request form, should you need it to satisfy your company's internal order procedures.

    Ordering Information

    Orders are processed immediately and you will be notified of the despatch date on confirmation of your order.

    Accepted Card Types


    Buy now using our secure payment system.

    We Stock...