Sinusitis - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Sinusitis - Pipeline Review, H2 2020, provides an overview of the Sinusitis (Ear Nose Throat Disorders) pipeline landscape.Sinusitis is characterized by inflammation of the sinuses. This inflammation usually stems from infection caused by a viral or bacterial infection or by an allergy Symptoms include congestion and obstruction in the nose, pain, tenderness, hyposmia, h

Tinnitus - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Tinnitus - Pipeline Review, H2 2020, provides an overview of the Tinnitus (Ear Nose Throat Disorders) pipeline landscape.Tinnitus is a condition characterized by ringing, swishing, or other noises that originating in the ear or head. Causes of tinnitus are age-related hearing loss, exposure to loud noises, earwax blockage in the ear canal, smoking and abnormal bone growth

Celiac Disease - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Celiac Disease - Pipeline Review, H2 2020, provides an overview of the Celiac Disease (Gastrointestinal) pipeline landscape.Celiac disease is an autoimmune disorder caused by an immune response to wheat protein gluten. Symptoms include weight loss, vomiting, abdominal bloating, abdominal pain and persistent diarrhea. Risk factors include lupus, rheumatoid arthritis,

Alcoholic Hepatitis - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Alcoholic Hepatitis - Pipeline Review, H2 2020, provides an overview of the Alcoholic Hepatitis (Gastrointestinal) pipeline landscape.Alcoholic hepatitis is an inflammation of the liver. It is typically caused by excessive alcohol consumption over a long period of time. Symptoms include changes in appetite, dry mouth, weight loss, yellowing of the skin or eyes

Pancreatitis - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Pancreatitis - Pipeline Review, H2 2020, provides an overview of the Pancreatitis (Gastrointestinal) pipeline landscape.Pancreatitis is an inflammation of pancreas. Symptoms include upper abdominal pain, nausea, vomiting, and tenderness when touching the abdomen, weight loss and upper abdominal pain. Predisposing factors include alcoholism, smoking, family history of

Gastric Ulcers - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Gastric Ulcers - Pipeline Review, H2 2020, provides an overview of the Gastric Ulcers (Gastrointestinal) pipeline landscape.Gastric ulcer is a painful sore or ulcer in the lining of stomach. The most common cause of gastric ulcer is Helicobacter pylori bacterial infection. Symptoms include pain, bloating, retching, nausea or vomiting and unexplained weight loss. Pre

Fragile X Syndrome - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Fragile X Syndrome - Pipeline Review, H2 2020, provides an overview of the Fragile X Syndrome (Genetic Disorders) pipeline landscape.Fragile X syndrome is a genetic condition that causes a range of developmental problems including learning disabilities and cognitive impairment. Fragile X syndrome is caused by a change in a gene called FMR1. Fragile X syndrome oc

Leber Congenital Amaurosis (LCA) - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Leber Congenital Amaurosis - Pipeline Review, H2 2020, provides an overview of the Leber Congenital Amaurosis (Genetic Disorders) pipeline landscape.Leber congenital amaurosis is an eye disorder that primarily affects the retina, which is the specialized tissue at the back of the eye that detects light and color. This condition is the most common c

Glomerulonephritis - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Glomerulonephritis - Pipeline Review, H2 2020, provides an overview of the Glomerulonephritis (Genito Urinary System And Sex Hormones) pipeline landscape.Glomerulonephritis is also known as glomerular nephritis (GN) or glomerular disease. It is a disease of the kidney, characterized by inflammation of the glomeruli. Causes of glomerulonephritis include Streptoco

Hemophilia B (Factor IX Deficiency) - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Hemophilia B - Pipeline Review, H2 2020, provides an overview of the Hemophilia B (Hematological Disorders) pipeline landscape.Hemophilia B is a hereditary bleeding disorder caused by a lack of blood clotting factor IX. Symptoms include bleeding into joints and associated pain and swelling, bruising, excessive bleeding following circumcision, ga

Paroxysmal Nocturnal Hemoglobinuria - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Paroxysmal Nocturnal Hemoglobinuria - Pipeline Review, H2 2020, provides an overview of the Paroxysmal Nocturnal Hemoglobinuria (Hematological Disorders) pipeline landscape.Paroxysmal nocturnal hemoglobinuria is a rare disease in which red blood cells break down earlier than normal. Symptoms include abdominal pain, back pain, dark urine, easy br

Neutropenia - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Neutropenia - Pipeline Review, H2 2020, provides an overview of the Neutropenia (Hematological Disorders) pipeline landscape.Neutropenia is an abnormally low count of neutrophils, a type of white blood cell that helps fight off infections, particularly those caused by bacteria and fungi. Signs and symptoms include fevers, frequent infections, mouth ulcers, gum infectio

Acromegaly - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Acromegaly - Pipeline Review, H2 2020, provides an overview of the Acromegaly (Hormonal Disorders) pipeline landscape.Acromegaly is a hormonal disorder that develops when pituitary gland produces too much growth hormone during adulthood. Symptoms include body odor, easy fatigue, headache, large feet, excessive height, swelling of the bony areas around a joint, widely sp

Psoriasis - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Psoriasis - Pipeline Review, H2 2020, provides an overview of the Psoriasis (Immunology) pipeline landscape.Psoriasis is a chronic skin condition caused by an overactive immune system. Symptoms of the disease include shedding of cells, flared up skin, itchiness, and burning sensation, swollen and stiff joints. Predisposing factors include heredity, side effects of certai

Graft Versus Host Disease (GVHD) - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Graft Versus Host Disease - Pipeline Review, H2 2020, provides an overview of the Graft Versus Host Disease (Immunology) pipeline landscape.Graft-versus-host disease (GVHD) is a complication that can occur after a stem cell or bone marrow transplant in which the newly transplanted donor cells attack the transplant recipient's body. Symptoms include

Liver Transplant Rejection - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Liver Transplant Rejection - Pipeline Review, H2 2020, provides an overview of the Liver Transplant Rejection (Immunology) pipeline landscape.Liver transplantation is the conventional therapy used in various liver diseases. Liver has the unique ability to regenerate or grow, unlike any other organ in the body. Liver transplant replaces an injured or dise

Chlamydia Infections - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Chlamydia Infections - Pipeline Review, H2 2020, provides an overview of the Chlamydia Infections (Infectious Disease) pipeline landscape.Chlamydia is a sexually transmitted infection caused by a bacterium. Symptoms include burning feeling during urination, discharge from the penis or vagina, pain in the lower abdomen, bleeding between periods and pain and swe

Resistant Pseudomonas aeruginosa Infections - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Resistant Pseudomonas aeruginosa Infections - Pipeline Review, H2 2020, provides an overview of the Resistant Pseudomonas aeruginosa Infections (Infectious Disease) pipeline landscape.Pseudomonas aeruginosa has become an important cause of infection, especially in patients with compromised host defense mechanisms. It has an ability to ra

Tetanus - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Tetanus - Pipeline Review, H2 2020, provides an overview of the Tetanus (Infectious Disease) pipeline landscape.Tetanus is a serious illness caused by Clostridium bacteria. Signs and symptoms of tetanus include spasms and stiffness in jaw muscles, difficulty swallowing, stiffness of abdominal muscles, fever, sweating, elevated blood pressure and rapid heart rate. The predi

Schistosomiasis - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Schistosomiasis - Pipeline Review, H2 2020, provides an overview of the Schistosomiasis (Infectious Disease) pipeline landscape.Schistosomiasis is a type of infection caused by parasites that live in fresh water, such as rivers or lakes. Symptoms include a high temperature, headache, cough, a dark red, blotchy, raised skin rash, pain in the abdomen and joint and mu

Hepatitis C - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Hepatitis C - Pipeline Review, H2 2020, provides an overview of the Hepatitis C (Infectious Disease) pipeline landscape.Hepatitis C is a contagious viral infection affecting the liver. It may spread on contact with infected blood. It may be a mild condition or may extend over a longer span of time leading to various complications. The characteristic symptoms include ab

Herpes Zoster (Shingles) - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Herpes Zoster - Pipeline Review, H2 2020, provides an overview of the Herpes Zoster (Infectious Disease) pipeline landscape.Shingles (herpes zoster) is a painful, blistering skin rash. It is caused by the varicella-zoster virus. Symptoms may include fever and chills, headache, joint pain and swollen glands. The predisposing factors include age and weakened

Proliferative Diabetic Retinopathy (PDR) - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Proliferative Diabetic Retinopathy - Pipeline Review, H2 2020, provides an overview of the Proliferative Diabetic Retinopathy (Metabolic Disorders) pipeline landscape.Proliferative diabetic retinopathy (PDR) is the most severe type of diabetic retinopathy. Proliferative diabetic retinopathy occurs where fragile new blood vessels form on the

Hyperuricemia - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Hyperuricemia - Pipeline Review, H2 2020, provides an overview of the Hyperuricemia (Metabolic Disorders) pipeline landscape.High uric acid level, or hyperuricemia, is an excess of uric acid in blood. Symptoms include joints become swollen, tender and red, fever, chills, fatigue and kidney problems (caused by formation of kidney stones), or problems with urination. P

Post-Polycythemia Vera Myelofibrosis (PPV-MF) - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Post-Polycythemia Vera Myelofibrosis - Pipeline Review, H2 2020, provides an overview of the Post-Polycythemia Vera Myelofibrosis (Oncology) pipeline landscape.Post-Polycythemia Vera Myelofibrosis (PPV-MF) is a myeloproliferative blood cancer in which the bone marrow makes too many red blood cells. It may also result in the overproduct

Oligodendroglioma - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Oligodendroglioma - Pipeline Review, H2 2020, provides an overview of the Oligodendroglioma (Oncology) pipeline landscape.Oligodendroglioma is a type of glioma (primary glial brain tumor). They often contain mineral deposits (called calcifications), areas of hemorrhage, and/or cysts. The most common symptoms are seizures, headaches, and personality changes. Other

Esophageal Cancer - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Esophageal Cancer - Pipeline Review, H2 2020, provides an overview of the Esophageal Cancer (Oncology) pipeline landscape.Esophageal cancer is cancer that occurs in the esophagus. Symptoms include cough, difficulty swallowing, chest pain, pressure or burning and weight loss. Predisposing factors include age, smoking, obesity and bile reflux. Treatment includes ch

Human Papillomavirus (HPV) Associated Cancer - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Human Papillomavirus (HPV) Associated Cancer - Pipeline Review, H2 2020, provides an overview of the Human Papillomavirus (HPV) Associated Cancer (Oncology) pipeline landscape.Human papillomavirus (HPV) is the most common viral infection of the reproductive tract. Human papillomavirus (HPV) has been found to be associated with several t

Uveal Melanoma - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Uveal Melanoma - Pipeline Review, H2 2020, provides an overview of the Uveal Melanoma (Oncology) pipeline landscape.Uveal melanoma, the most common intraocular tumor, is a disease in which cancer (malignant) cells are found in the part of the eye called the uvea. The uvea contains cells called melanocytes. When these cells become cancerous, the cancer is called a me

Peritoneal Cancer - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Peritoneal Cancer - Pipeline Review, H2 2020, provides an overview of the Peritoneal Cancer (Oncology) pipeline landscape.Peritoneal cancer is a rare cancer that develops in the peritoneum, a thin, delicate sheet that lines the inside wall of the abdomen and covers the uterus and extends over the bladder and rectum. Peritoneal cancer usually manifests with abdomi

Rhabdomyosarcoma - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Rhabdomyosarcoma - Pipeline Review, H2 2020, provides an overview of the Rhabdomyosarcoma (Oncology) pipeline landscape.Rhabdomyosarcoma (RMS) is a malignant tumor of connective tissue in which abnormal cells are thought to arise from primitive muscle cells. Symptoms include pain, fever, purplish discoloration of the eye, hearing loss, headaches, bulging of the ey

Bacterial Conjunctivitis - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Bacterial Conjunctivitis - Pipeline Review, H2 2020, provides an overview of the Bacterial Conjunctivitis (Ophthalmology) pipeline landscape.Bacterial conjunctivitis is an inflammation of the conjunctiva caused by pathogenic bacteria. Bacterial conjunctivitis is usually caused by Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus sp, or, less com

Glaucoma - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Glaucoma - Pipeline Review, H2 2020, provides an overview of the Glaucoma (Ophthalmology) pipeline landscape.Glaucoma is a disease of the eye in which fluid pressure within the eye rises. The exact cause of optic nerve damage from glaucoma is not fully understood, but involves mechanical compression and/or decreased blood flow of the optic nerve. The most important risk f

Keratoconjunctivitis sicca (Dry Eye) - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Keratoconjunctivitis Sicca - Pipeline Review, H2 2020, provides an overview of the Keratoconjunctivitis Sicca (Ophthalmology) pipeline landscape.Keratoconjunctivitis sicca (KCS) or dry eye disease (DED) or dry eye syndrome (DES) is a condition in which a person experience desiccation of the conjunctiva and cornea due to an inadequate tear film.

Uveitis - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Uveitis - Pipeline Review, H2 2020, provides an overview of the Uveitis (Ophthalmology) pipeline landscape.Uveitis is swelling and irritation of the uvea, the middle layer of the eye. Uveitis can affect one or both eyes. Uveitis can be caused by autoimmune disorders such as rheumatoid arthritis or ankylosing spondylitis, infection, or exposure to toxins. Symptoms include b

Leber’s Hereditary Optic Neuropathy (Leber Optic Atrophy) - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Leber’s Hereditary Optic Neuropathy - Pipeline Review, H2 2020, provides an overview of the Leber’s Hereditary Optic Neuropathy (Ophthalmology) pipeline landscape.Leber’s hereditary optic neuropathy (LHON) is an inherited form of vision loss. This condition usually begins in a person's teens or twenties, rare cases

Retinopathy Of Prematurity - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Retinopathy Of Prematurity - Pipeline Review, H2 2020, provides an overview of the Retinopathy Of Prematurity (Ophthalmology) pipeline landscape.Retinopathy of prematurity (ROP) is a disease that affects immature vasculature in the eyes of premature babies. This disorder which usually develops in both eyes is one of the most common causes of visual loss

Pancreatic Cancer - Pipeline Review, H2 2020SummaryGlobal Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Pancreatic Cancer - Pipeline Review, H2 2020, provides an overview of the Pancreatic Cancer (Oncology) pipeline landscape.Pancreatic cancer is a disease in which malignant (cancer) cells are found in the tissues of the pancreas. This is also called exocrine cancer. Signs and symptoms include upper abdominal pain that may radiate to back, yellowing of skin and the

Aryl Hydrocarbon Receptor - Pipeline Review, H2 2020SummaryAryl Hydrocarbon Receptor (Class E Basic Helix Loop Helix Protein 76 or bHLHe76 or AHR) pipeline Target constitutes close to 27 molecules. Out of which approximately 24 molecules are developed by companies and remaining by the universities/institutes. The latest report Aryl Hydrocarbon Receptor - Pipeline Review, H2 2020, outlays comprehensive information on the Aryl Hydrocarbon Receptor (Class E Basic Helix Loop Helix Protein 76 or bHLH

Bromodomain Testis Specific Protein - Pipeline Review, H2 2020SummaryBromodomain Testis Specific Protein (Cancer/Testis Antigen 9 or RING3 Like Protein or BRDT) - Bromodomain testis-specific protein is a protein encoded by the BRDT gene. It plays a role in meiotic and post-meiotic cells by binding to acetylated histones at the promoter of specific meiotic and post-meiotic genes, facilitating their activation at the appropriate time. It binds to hyperacetylated histones and participates in their

5-Hydroxytryptamine Receptor 2B - Pipeline Review, H2 2020SummaryAccording to the recently published report '5-Hydroxytryptamine Receptor 2B - Pipeline Review, H2 2020'; 5-Hydroxytryptamine Receptor 2B (5 HT2B or Serotonin Receptor 2B or HTR2B) pipeline Target constitutes close to 8 molecules. 5-Hydroxytryptamine Receptor 2B (5 HT2B or Serotonin Receptor 2B or HTR2B) - 5-Hydroxytryptamine receptor 2B (5-HT2B) or serotonin receptor 2B is a protein encoded by the HTR2B gene. It plays a role in the

5-Hydroxytryptamine Receptor 7 - Pipeline Review, H2 2020Summary5-Hydroxytryptamine Receptor 7 (5 HT7 or 5 HTX or Serotonin Receptor 7 or HTR7) pipeline Target constitutes close to 13 molecules. Out of which approximately 12 molecules are developed by companies and remaining by the universities/institutes. The latest report 5-Hydroxytryptamine Receptor 7 - Pipeline Review, H2 2020, outlays comprehensive information on the 5-Hydroxytryptamine Receptor 7 (5 HT7 or 5 HTX or Serotonin Receptor 7 or

Gamma-Aminobutyric Acid Receptor Subunit Alpha 3 - Pipeline Review, H2 2020SummaryGamma-Aminobutyric Acid Receptor Subunit Alpha 3 (GABA(A) Receptor Subunit Alpha 3 or GABRA3) - Gamma-aminobutyric acid receptor subunit alpha-3 is a protein that encoded by the GABRA3 gene. It mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.Gamma-Aminobutyric Acid Receptor Subunit Alpha 3 (GABA(A) Receptor Subunit Alpha 3 or GABRA3) pipeline Targ

Gamma-Aminobutyric Acid Receptor Subunit Alpha 5 - Pipeline Review, H2 2020SummaryAccording to the recently published report 'Gamma-Aminobutyric Acid Receptor Subunit Alpha 5 - Pipeline Review, H2 2020'; Gamma-Aminobutyric Acid Receptor Subunit Alpha 5 (GABA(A) Receptor Subunit Alpha 5 or GABRA5) pipeline Target constitutes close to 12 molecules. Out of which approximately 10 molecules are developed by companies and remaining by the universities/institutes. Gamma-Aminobutyric Acid Receptor Subun

Heparanase - Pipeline Review, H2 2020SummaryHeparanase (Endo Glucoronidase or Heparanase 1 or HPSE or EC 3.2.1.166) pipeline Target constitutes close to 12 molecules. Out of which approximately 10 molecules are developed by companies and remaining by the universities/institutes. The latest report Heparanase - Pipeline Review, H2 2020, outlays comprehensive information on the Heparanase (Endo Glucoronidase or Heparanase 1 or HPSE or EC 3.2.1.166) targeted therapeutics, complete with analysis by i

High Mobility Group Protein B1 - Pipeline Review, H2 2020SummaryHigh Mobility Group Protein B1 (High Mobility Group Protein 1 or High Mobility Group Protein Box 1 or HMGB1) - High mobility group box 1 protein also known as high-mobility group protein 1 (HMG-1) is a protein encoded by the HMGB1 gene.HMGB1 is secreted by immune cells like macrophages, monocytes and dendritic cells through leaderless secretory pathway. Activated macrophages and monocytes secrete HMGB1. The mechanism of inflammation

Calcitonin Gene Related Peptide - Pipeline Review, H2 2020SummaryAccording to the recently published report 'Calcitonin Gene Related Peptide - Pipeline Review, H2 2020'; Calcitonin Gene Related Peptide (CGRP) pipeline Target constitutes close to 12 molecules. Out of which approximately 11 molecules are developed by companies and remaining by the universities/institutes. Calcitonin Gene Related Peptide (CGRP) - Calcitonin gene related peptide (CGRP) is a member of the calcitonin family of peptide

C-C Chemokine Receptor Type 4 - Pipeline Review, H2 2020SummaryC-C Chemokine Receptor Type 4 (K5-5 or CD194 or CCR4) pipeline Target constitutes close to 9 molecules. Out of which approximately 8 molecules are developed by companies and remaining by the universities/institutes. The latest report C-C Chemokine Receptor Type 4 - Pipeline Review, H2 2020, outlays comprehensive information on the C-C Chemokine Receptor Type 4 (K5-5 or CD194 or CCR4) targeted therapeutics, complete with analysis by i