DailyUpdates was launched in 2002 by the pharmaceutical analysts LeadDiscovery and represents the first "newsfeed" that identifies breaking scientific publications with drug development potential. Using proprietary data retrieval strategies LeadDiscovery selects daily 1,000 PubMed articles and press releases. The selected articles and releases are then scanned by an industrial research panel which judges those articles considered to be of greatest benefit for the drug development sector. Selected publications as well as press releases are then listed on DailyUpdates six therapeutic channels that match core R&D areas; Oncology Channel; CNS disorders; Cardiovascular disease; Metabolic and Hormonal disorders; Immunology, Inflammation & Infection; Internal Medicine.
Subscription to this service is $95.00/year per channel. From the day of your subscription you will receive daily email bulletins (see Oncology sample below) specific to your selected channel delivering:
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DailyUpdates by e-mail - the publication tracker for the drug discovery community
Oncology Channel - sample 30th March 2004
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Today's top news stories Cell Genesys Reports Synergistic Antitumor Activity for GVAX(R) Cancer Vaccine Plus Docetaxel Chemotherapy in Preclinical Studies EntreMed's Immunomodulator Induces Long-Term Anti-Tumor Activity in Preclinical Models Aegera Initiates Phase 1 Oncology Clinical Trial of XIAP Antisense Designed to Stimulate Apoptotic Cell Death in Cancer Cells CombinatoRx Presents Dual Action Anti-Cancer Drug at AACR Conference Peregrine's VTA & Docetaxel Combination Therapy Inhibits Human Breast Cancer Growth by 93% in Pre-Clinical Studies Exelixis Describes the Discovery of Novel Cancer Targets at AACR Array BioPharma Release: Investigational MEK Inhibitor, ARRY-142886 (AZD6244), Combats Cancer Growth NeoPharm Announces New Approach For Combination Therapy By Entrapping Two Drugs In Single Liposome Using NeoLipid Technology Oxigene shares up as cancer drug effective in mice All of today's news stories updated every 30 minutes Submit your press release or have LeadDiscovery produce a release for you PharmaReports Click here for our full list of PharmaReports Submit your publication to DailyUpdates Subscription to targeted DailyUpdates channels
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Recent journal articles featuring Licensing/Collaborative opportunities Direct injection of immature dendritic cells into irradiated tumor induces efficient antitumor immunity. Int J Cancer. 2004 May 1;109(5):685-90. Most recent journal article entries Synthesis and biological activity of selective azasugar-based TACE inhibitors. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1569-72. Non-peptide alpha v beta 3 antagonists. Part 7: 3-Substituted tetrahydro-naphthyridine derivatives. Bioorg Med Chem Lett. 2004 Feb 23;14(4):1049-52. Hepatic gene expression of NK4, an HGF-antagonist/angiogenesis inhibitor, suppresses liver metastasis and invasive growth of colon cancer in mice. Cancer Gene Ther. 2004 Mar 12 [Epub ahead of print]. Novel Gemini analogs of 1alpha,25-dihydroxyvitamin D(3) with enhanced transcriptional activity. Biochem Pharmacol. 2004 Apr 1;67(7):1327-36. Syntheses and EGFR kinase inhibitory activity of 6-substituted-4-anilino [1,7] and [1,8] naphthyridine-3-carbonitriles. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1411-6 Design and synthesis of 3,7-diarylimidazopyridines as inhibitors of the VEGF-receptor KDR. Bioorg Med Chem Lett. 2004 Feb 23;14(4):909-12. Pharmacogenomic profiling of the PI3K/PTEN-AKT-mTOR pathway in common human tumors. Int J Oncol. 2004 Apr;24(4):893-900. Selected analyses of pharmaceutical/market development relating to today's selected publications (click on title or the
Previous entries Vaccination of patients with advanced ovarian carcinoma with the anti-idiotype ACA125: immunological response and survival (phase Ib/II). Clin Cancer Res. 2004 Mar 1;10(5):1580-7. Complete response of severe symptomatic bone marrow metastases from heavily pretreated breast cancer with a 3-weekly trastuzumab schedule. A clinical case. Anticancer Res. 2004 Jan-Feb;24(1):317-9. Blockage of 2-deoxy-D-ribose-induced angiogenesis with rapamycin counteracts a thymidine phosphorylase-based escape mechanism available for colon cancer under 5-fluorouracil therapy. Clin Cancer Res. 2004 Mar 1;10(5):1843-52.
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