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The Caspase-1 Inflammasome & its Role in Autoinflammatory Diseases - R&D Systems
20,27,29 Recent studies in patients with type 2 diabetes reveal that the administration of IL-1ra, Anakinra, protects insulin-secreting beta cells in the pancreatic islet.
30 These clinical findings confirm studies published over 20 years ago that indicate IL-1 beta is toxic for the beta cell and participates in the loss of beta cell mass in diabetes.
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Transcription Factors & Regulators - R&D Systems
PRODUCTS RESEARCH TOPICS BROWSE BY MOLECULE TECHNICAL INFORMATION CUSTOMER SERVICE HEMATOLOGY ABOUT US Cancer Development Endocrinology Glycobiology Immunology Neuroscience Proteases & Other Enzymes Signal Transduction Stem Cells Home | Research Topics | Cancer | Transcription Factors & Regulators Transcription Factors & Regulators
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Neurogenin-3 - R&D Systems
Neurogenin-3 expression is required for endocrine lineage differentiation in the pancreas, including formation of islet beta cells.
Products By Product Type All Products for this Molecule Antibodies RELATED INFORMATION Neural Crest Cell Markers Transcription Factors & Regulators USA-|-(800) 343-7475-|- Worldwide...
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Neurogenin-2 - R&D Systems
Neurogenin-3 expression is required for endocrine lineage differentiation in the pancreas, including formation of islet beta cells.
Products By Product Type All Products for this Molecule Antibodies RELATED INFORMATION Neural Crest Cell Markers Transcription Factors & Regulators USA-|-(800) 343-7475-|- Worldwide...
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Neurogenin-1 - R&D Systems
Neurogenin-3 expression is required for endocrine lineage differentiation in the pancreas, including formation of islet beta cells.
Products By Product Type All Products for this Molecule Antibodies RELATED INFORMATION Neural Crest Cell Markers Transcription Factors & Regulators USA-|-(800) 343-7475-|- Worldwide...
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LYVE-1: Functions & Use as a Lymphatic Marker - R&D Systems
PRODUCTS RESEARCH TOPICS BROWSE BY MOLECULE TECHNICAL INFORMATION CUSTOMER SERVICE HEMATOLOGY ABOUT US Literature New Product Release In Scope/Focus Cytokine Bulletin Minireviews Additional Literature Posters Request Literature Protocols Material Safety Data Sheets Additional Technical Support Home | Technical Information | Literature | Cytokine Bulletin | LYVE-1: Functions & Use as...
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Immunohistochemistry : Islet-1 - R&D Systems
PRODUCTS RESEARCH TOPICS BROWSE BY MOLECULE TECHNICAL INFORMATION CUSTOMER SERVICE HEMATOLOGY ABOUT US Literature Protocols Bioassay IHC Western Blot Stem Cell Protocols Enzyme Assays Material Safety Data Sheets Additional Technical Support Home | Technical Information | Protocols | IHC | IHC Images | IHC Molecule Images ...
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Autoimmunity Poster References, January 2006 - R&D Systems
Circulating autoantibodies to multiple islet antigens have been identified and are potential markers for T1D susceptibility.
Lymphocytes in the islets during recent onset T1D express IFN-?.
Recent onset T1D T cells in the islet express IFN-?
Islets in general Cardozo, A.K.

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Stem Cell Markers - R&D Systems
PRODUCTS RESEARCH TOPICS BROWSE BY MOLECULE TECHNICAL INFORMATION CUSTOMER SERVICE HEMATOLOGY ABOUT US Literature New Product Release In Scope/Focus Cytokine Bulletin Minireviews Additional Literature Posters Request Literature Protocols Material Safety Data Sheets Additional Technical Support Home | Technical Information | Literature | Minireviews | Stem Cell Markers STEM ...
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Transcription Factors & Regulators - R&D Systems
Transcription Factors AP-2 epsilon Miz-1/ZBTB17 AP-2 gamma MLX ATF1 MSX1 ATF2 Mxi1 beta-Catenin MYCL1 BLIMP1 Myocardin Brachyury Nanog c-Jun NeuroD1 c-Myc Neurogenin-1 CDX2 Neurogenin-2 CDX4 NFkB1 CLOCK NFkB2 CREB NKX2.5 CREG Nrf1 CSL Nrf2 DACH2 NRL DC-SCRIPT/ZNF366 Nurr-1/NR4A2 E2F-1 OASIS E2F-2 Oct-3/4 E2F-4 Olig 1, 2, 3 EBF-1 Olig1 EBF-3 Olig2 EGR1 Olig3 Elk-1 Otx2 Engrailed-2 p53...
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Transcription Factors & Regulators - R&D Systems
Transcription Factors AP-2 epsilon Miz-1/ZBTB17 AP-2 gamma MLX ATF1 MSX1 ATF2 Mxi1 beta-Catenin MYCL1 BLIMP1 Myocardin Brachyury Nanog c-Jun NeuroD1 c-Myc Neurogenin-1 CDX2 Neurogenin-2 CDX4 NFkB1 CLOCK NFkB2 CREB NKX2.5 CREG Nrf1 CSL Nrf2 DACH2 NRL DC-SCRIPT/ZNF366 Nurr-1/NR4A2 E2F-1 OASIS E2F-2 Oct-3/4 E2F-4 Olig 1, 2, 3 EBF-1 Olig1 EBF-3 Olig2 EGR1 Olig3 Elk-1 Otx2 Engrailed-2 p53...
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Transcription Factors & Regulators - R&D Systems
Transcription Factors AP-2 epsilon Miz-1/ZBTB17 AP-2 gamma MLX ATF1 MSX1 ATF2 Mxi1 beta-Catenin MYCL1 BLIMP1 Myocardin Brachyury Nanog c-Jun NeuroD1 c-Myc Neurogenin-1 CDX2 Neurogenin-2 CDX4 NFkB1 CLOCK NFkB2 CREB NKX2.5 CREG Nrf1 CSL Nrf2 DACH2 NRL DC-SCRIPT/ZNF366 Nurr-1/NR4A2 E2F-1 OASIS E2F-2 Oct-3/4 E2F-4 Olig 1, 2, 3 EBF-1 Olig1 EBF-3 Olig2 EGR1 Olig3 Elk-1 Otx2 Engrailed-2 p53...
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Nestin - R&D Systems
Nestin is also expressed in non-neural stem cell populations, such as pancreatic islet progenitors and hematopoietic progenitors.
Products By Product Type All Products for this Molecule Antibodies Primer Pairs RELATED INFORMATION Cancer Biomarkers Cancer Stem Cells Early Ectodermal Lineage Markers Immunohistochemistry...
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LYVE-1 - R&D Systems
In addition to hepatic and lymphatic endothelia, some expression of LYVE-1 has been reported on Kupffer cells, the islets of Langerhans, cortical neurons, and renal epithelium.
Products By Product Type All Products for this Molecule Antibodies Recombinant & Natural Proteins ELISA/Assay Development Kits & Reagents RELATED INFORMATION
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Kirrel2 - R&D Systems
Kirrel1 can also be found in central nervous system neurons, pancreas and placenta, Kirrel2 in pancreatic islet beta cells, brain and lymph nodes, and Kirrel3 in the brain and bone marrow, typically at sites where nephrin is also expressed.
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Islet-1 - R&D Systems
It is expressed in all islet cells in the pancreas and is an early marker for motor neuron differentiation.
Products By Product Type All Products for this Molecule Antibodies RELATED INFORMATION Immunohistochemistry: Islet-1 Motor Neuronal Markers Pancreatic Endoderm Transcription Factors & Regulators USA-|-(800) 343...
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Product Search Results - R&D Systems
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Transcription Factors & Regulators - R&D Systems
Transcription Factors AP-2 epsilon Miz-1/ZBTB17 AP-2 gamma MLX ATF1 MSX1 ATF2 Mxi1 beta-Catenin MYCL1 BLIMP1 Myocardin Brachyury Nanog c-Jun NeuroD1 c-Myc Neurogenin-1 CDX2 Neurogenin-2 CDX4 NFkB1 CLOCK NFkB2 CREB NKX2.5 CREG Nrf1 CSL Nrf2 DACH2 NRL DC-SCRIPT/ZNF366 Nurr-1/NR4A2 E2F-1 OASIS E2F-2 Oct-3/4 E2F-4 Olig 1, 2, 3 EBF-1 Olig1 EBF-3 Olig2 EGR1 Olig3 Elk-1 Otx2 Engrailed-2 p53...
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Transcription Factors & Regulators - R&D Systems
Transcription Factors AP-2 epsilon Miz-1/ZBTB17 AP-2 gamma MLX ATF1 MSX1 ATF2 Mxi1 beta-Catenin MYCL1 BLIMP1 Myocardin Brachyury Nanog c-Jun NeuroD1 c-Myc Neurogenin-1 CDX2 Neurogenin-2 CDX4 NFkB1 CLOCK NFkB2 CREB NKX2.5 CREG Nrf1 CSL Nrf2 DACH2 NRL DC-SCRIPT/ZNF366 Nurr-1/NR4A2 E2F-1 OASIS E2F-2 Oct-3/4 E2F-4 Olig 1, 2, 3 EBF-1 Olig1 EBF-3 Olig2 EGR1 Olig3 Elk-1 Otx2 Engrailed-2 p53...
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Citations Search
(1996) Prevention of adoptively transferred diabetes in nonobese diabetic mice with IL-10-transduced islet-specific Th1 lymphocytes: A gene therapy model for autoimmune diabetes.
- Notes: The inhibitor was used for protection of cells and colonies following RT-PCR.

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Citations Search
- Notes: The SV Total RNA Isolation System was used to isolate total RNA from normal skin, psoriatic skin, H-128 small cell lung carcinoma cells and peripheral blood mononuclear cells.
(1998) IL-1 produced and released endogenously within human islets inhibits beta cell function.

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Citations Search
- Notes: The SV Total RNA Isolation System was used to isolate total RNA from normal skin, psoriatic skin, H-128 small cell lung carcinoma cells and peripheral blood mononuclear cells.
(1998) IL-1 produced and released endogenously within human islets inhibits beta cell function.

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Citations Search
In Western blot analysis with Jurkat cells treated with an anti-Fas antibody and with SH-Sy5Y cells treated with staurosporine, the antibody recognizes the 85-kDa (p85) fragment of PARP but not full-length PARP.
(2001) Proteins linked to a protein transduction domain efficiently transduce pancreatic islets Diabetes 50 , 1706-1713.

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Citations Search
- Notes: A rat islet cell line stably expressing rat placental lactogen was generated.
- Notes: The CellTiter 96 A® AQueous Assay (MTS/PMS) was used to measure the proliferation of the DOV13 human ovarian epithelial cell carcinoma cell in the presence of n-terminal fragment of urinary-type plasminogen activator and antibodies to the fragment.<...
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Citations Search
In Western blot analysis with Jurkat cells treated with an anti-Fas antibody and with SH-Sy5Y cells treated with staurosporine, the antibody recognizes the 85-kDa (p85) fragment of PARP but not full-length PARP.
(2001) Proteins linked to a protein transduction domain efficiently transduce pancreatic islets Diabetes 50 , 1706-1713.

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