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Chemokine Family - R&D Systems
Chemokines mediate their activities by binding to target cell surface chemokine receptors that belong to the large family of G protein-coupled, seven transmembrane domain receptors.
Among CC chemokines family members, mouse MIP-1 gamma shares approximately 45%, 24% and 20% aa sequence identity with mouse C10, mouse MIP-1 alpha and...
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Multiple Sclerosis: Immune Cell Access to the Central Nervous System - R&D Systems
88-91 Several in vitro studies have suggested that ICAM-1 activity is important for the interaction of leukocytes with brain endothelia, and may be enhanced by the accompanied activation of the Gi subtype of G protein-coupled receptors.
129,130 Chemokine activities are mediated via a subset of 7 transmembrane domain G protein-coupled ...
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Wnt Receptors and Pathways - R&D Systems
44,45 Frizzled-3 Human Frizzled-3 is a 666 aa, seven-TM, G protein-coupled receptor that contains a 17 aa signal sequence, a 188 aa N-terminal region, and a lengthy 168 aa C-terminal tail.
56 Frizzled-9 Frizzled-9 is a 569 aa, G protein-coupled receptor that contains a 207 aa N-terminus, seven TM segments, and a 62 aa C...
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Citations Search
(0000495) - - Products: Erase-a-Base ® System (minus vectors & bacterial strain) | Luciferase Assay System | pGL3-Basic Vector | T N T ® SP6 Coupled Reticulocyte Lysate System 78.
- Notes: Intravenous somatic gene transfer with an expression plasmid coding for IκBα was used to investigate the role of members of the NFκB family in a mouse...
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Citations Search
The promoters of 4 MCT family members (MCT1, MCT2, MCT3 and MCT4), were amplified by PCR and cloned into the pGEM A® -T Easy Vector.
(0003460) - - Products: Dual-Luciferase ® Reporter Assay System | Dual-Luciferase ® Reporter Assay System 10-Pack | FluoroTect™ GreenLys in vitro Translation Labeling System | pGEM ® -7Zf(–) Vector | pGEM &...
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Citations Search
(0000495) - - Products: Erase-a-Base ® System (minus vectors & bacterial strain) | Luciferase Assay System | pGL3-Basic Vector | T N T ® SP6 Coupled Reticulocyte Lysate System 78.
- Notes: Intravenous somatic gene transfer with an expression plasmid coding for IκBα was used to investigate the role of members of the NFκB family in a mouse...
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Citations Search
- Notes: This study examined both the human and the macaque counterparts of the Mas-related genes (Mrg), a family of G-protein-coupled receptors, in assays to compare function and structure.
The promoters of 4 MCT family members (MCT1, MCT2, MCT3 and MCT4), were amplified by PCR and cloned into the pGEM A® -T Easy Vector.
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Citations Search
In vivo cyclin-mediated phosphorylation was assayed by cotransfecting the RB expression plasmids with members of the cyclin D or cyclin E family into an RB (-/-) cell line.
(1998) Cloning and characterization of the Hakata antigen, a member of the ficolin/opsonin p35 lectin family.
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Citations Search
- Notes: This paper investigates the mechanism of estrogen receptor alpha (ERalpha) degradation.-Loss of ER- is associated with aggressive breast tumors and poor clinical outcome.-ERK7 is shown to be a specific regulator of ERalpha degradation in human breast cells.- Several members of the MAPK family were examined to determine if they regulate ERK7 turnover.
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Citations Search
The promoters of 4 MCT family members (MCT1, MCT2, MCT3 and MCT4), were amplified by PCR and cloned into the pGEM A® -T Easy Vector.
(0003460) - - Products: Dual-Luciferase ® Reporter Assay System | Dual-Luciferase ® Reporter Assay System 10-Pack | FluoroTect™ GreenLys in vitro Translation Labeling System | pGEM ® -7Zf(–) Vector | pGEM &...
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Citations Search
- Notes: This study examined both the human and the macaque counterparts of the Mas-related genes (Mrg), a family of G-protein-coupled receptors, in assays to compare function and structure.
The promoters of 4 MCT family members (MCT1, MCT2, MCT3 and MCT4), were amplified by PCR and cloned into the pGEM A® -T Easy Vector.
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Citations Search
In vivo cyclin-mediated phosphorylation was assayed by cotransfecting the RB expression plasmids with members of the cyclin D or cyclin E family into an RB (-/-) cell line.
(1998) Cloning and characterization of the Hakata antigen, a member of the ficolin/opsonin p35 lectin family.
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Citations Search
- Notes: This paper investigates the mechanism of estrogen receptor alpha (ERalpha) degradation.-Loss of ER- is associated with aggressive breast tumors and poor clinical outcome.-ERK7 is shown to be a specific regulator of ERalpha degradation in human breast cells.- Several members of the MAPK family were examined to determine if they regulate ERK7 turnover.
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Citations Search
- Notes: This article examines the interaction between CAR, a member of the nuclear steroid/thyroid hormone receptor family, which translocates from the cytoplasm to the nucleus when cells are exposed to phenobaritol, and the membrane-associated subunit of protein phosphatase 1 (PPP1R16A, or abbreviated as R16A), which is a novel CAR-binding protein.<...
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Citations Search
- Notes: This paper investigates the mechanism of estrogen receptor alpha (ERalpha) degradation.-Loss of ER- is associated with aggressive breast tumors and poor clinical outcome.-ERK7 is shown to be a specific regulator of ERalpha degradation in human breast cells.- Several members of the MAPK family were examined to determine if they regulate ERK7 turnover.
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Citations Search
- Notes: This paper investigates the mechanism of estrogen receptor alpha (ERalpha) degradation.-Loss of ER- is associated with aggressive breast tumors and poor clinical outcome.-ERK7 is shown to be a specific regulator of ERalpha degradation in human breast cells.- Several members of the MAPK family were examined to determine if they regulate ERK7 turnover.
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Citations Search
- Notes: This paper investigates the mechanism of estrogen receptor alpha (ERalpha) degradation.-Loss of ER- is associated with aggressive breast tumors and poor clinical outcome.-ERK7 is shown to be a specific regulator of ERalpha degradation in human breast cells.- Several members of the MAPK family were examined to determine if they regulate ERK7 turnover.
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Apoptosis Protocols and Applications Guide
Pro-apoptotic signals direct the Group II and III Bcl-2 family proteins to the mitochondria where the pro-apoptotic members interact with anti-apoptotic Bcl-2 family members including Bcl-2 and Bcl-XL to determine whether or not apoptosis will be initiated.
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TRPC6 Antibody (NT) Short transient receptor potential channel 6
The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types..
Furthermore, the members of the TRPC6/6/7 subfamily can be activated by diacylglycerol (DAG) analogs, suggesting a possible mechanism of activation of these...
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TRPC6 Antibody (CT) Short transient receptor potential channel 6
The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types (1).
Furthermore, the members of the TRPC6/6/7 subfamily can be activated by diacylglycerol (DAG) analogs, suggesting a possible mechanism of activation of...
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pCLIP-NK1R Control Plasmid(N9214), Plasmids and Controls, NEB
Download: MSDS PDF Description: This control plasmid contains the gene encoding the seven-pass transmembrane protein Neurokinin-1 receptor (NK1R), a member of the G-protein coupled receptor family.
In the labeling reaction, the substituted benzyl group of the substrate is covalently attached to the reactive cysteine of CLIP-tag...
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Probes for Neurotransmitter Receptors - Section 16.2
Abbreviations: RAC/Gs = Receptors coupled to G-proteins that stimulate adenylate cyclase (AC) activity, leading to cAMP formation and enhanced activity of protein kinase A (PKA).
Substance P Analogs Substance P is an agonist of the neurokinin 1 (NK1) receptor, a member of the seven-domain transmembrane G-protein–coupled ...
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Detecting Enzymes That Metabolize Phosphates and Polyphosphates - Section 10.3
#rightRTE blockquote { margin-left: 10px; margin-right: 10px } #mainRTE blockquote { margin-left: 20px; margin-right: 20px } BODIPY FL ATP-I³-S and BODIPY FL GTP-I³-S Thioesters: Substrates for the Fhit Nucleotide-Binding Protein #rightRTE blockquote { margin-left: 10px; margin-right: 10px } #mainRTE blockquote { margin-left: 20px; margin-right: 20px } The Patented...
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Probes for Neurotransmitter Receptors - Section 16.2
Abbreviations: RAC/Gs = Receptors coupled to G-proteins that stimulate adenylate cyclase (AC) activity, leading to cAMP formation and enhanced activity of protein kinase A (PKA).
Substance P Analogs Substance P is an agonist of the neurokinin 1 (NK1) receptor, a member of the seven-domain transmembrane G-protein–coupled ...
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Detecting Enzymes That Metabolize Phosphates and Polyphosphates - Section 10.3
#rightRTE blockquote { margin-left: 10px; margin-right: 10px } #mainRTE blockquote { margin-left: 20px; margin-right: 20px } BODIPY FL ATP-I³-S and BODIPY FL GTP-I³-S Thioesters: Substrates for the Fhit Nucleotide-Binding Protein #rightRTE blockquote { margin-left: 10px; margin-right: 10px } #mainRTE blockquote { margin-left: 20px; margin-right: 20px } The Patented...
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