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Clinical Challenges in Addressing Resistance to Antimicrobial Drugs in the Twenty-First Century
Clinical Pharmacology & Therapeutics, 07/02/09 Print Save in My Library Free Abstract Septimus EJ et al.- Among the gram-positive pathogens, methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus...
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Promising Year Ahead for Optimer Pharma
Optimer Pharmaceuticals (OPTR) recently announced results from the phase III clinical study of fidaxomicin in patients with Clostridium difficile-associated diarrhea (CDAD) at the Digestive Disease Week 2009 conference in Chicago.The data...
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Multicenter, Randomized Study of the Efficacy and Safety of Intravenous Iclaprim in Complicated Skin and Skin
Antimicrobial Agents and Chemotherapy, 06/26/09 Print Save in My Library Free Abstract Krievins D et al.- Iclaprim exhibited a safety profile similar to that of vancomycin, an established drug for the treatment of cSSSI. Results...
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Multicenter, Randomized Study of the Efficacy and Safety of Intravenous Iclaprim in Complicated Skin and Skin
Iclaprim is a novel antibacterial agent that is currently in development for the treatment of complicated skin and skin structure infections (cSSSI).Iclaprim specifically and selectively inhibits bacterial dihydrofolate reductase, a...
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Nine-Hospital Study Comparing Broth Microdilution and Etest Method Results for Vancomycin and Daptomycin again
Antimicrobial Agents and Chemotherapy, July 2009, p.3162-3165, Vol. 53, No. 7 Copyright 2009, American Society for Microbiology. All Rights Reserved. Helio S. Sader,* Paul R. Rhomberg, and Ronald N. Jones JMI Laboratories,...
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Activity of Telavancin against Staphylococcus aureus Strains with Various Vancomycin Susceptibilities in an In
We investigated the activity of telavancin, a novel lipoglycopeptide, alone and combined with gentamicin or rifampin (rifampicin) against strains of Staphylococcus aureus with various vancomycin susceptibilities.Strains tested...
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Comparison of Tigecycline and Vancomycin for Treatment of Experimental Foreign-Body Infection Due to Methicill
Antimicrobial Agents and Chemotherapy, July 2009, p.3150-3152, Vol. 53, No. 7 Copyright 2009, American Society for Microbiology. All Rights Reserved. Pierre Vaudaux,* Bndicte Fleury, Asllan Gjinovci, Elzbieta Huggler, Manuela...
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Noncanonical Vancomycin Resistance Cluster from Desulfitobacterium hafniense Y51
The glycopeptide vancomycin is a drug of last resort for infection with gram-positive organisms, and three genes are vital to resistance: vanH, vanA, and vanX.These genes are found in a vanHAX cluster, which is conserved across...
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In Vitro Activities of Telavancin and Vancomycin against Biofilm-Producing Staphylococcus aureus, S. epidermid
In Vitro Activities of Telavancin and Vancomycin against Biofilm-Producing Staph In Vitro Activities of Telavancin and Vancomycin against Biofilm-Producing Staphylococcus aureus, S.epidermid.
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Resistance Selection Studies Comparing the Activity of Razupenem (PTZ601) to Vancomycin and Linezolid against
Antimicrobial Agents and Chemotherapy, July 2009, p.3118-3121, Vol. 53, No. 7 Copyright 2009, American Society for Microbiology. All Rights Reserved. Catherine Clark, Klaudia Kosowska-Shick, Pamela McGhee, Bonifacio Dewasse, Linda...
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Efficacy of Daptomycin in Implant-Associated Infection Due to Methicillin-Resistant Staphylococcus aureus: Imp
Infectious Diseases, Department of Biomedicine, University Hospital Basel, Basel, Switzerland,1 Division of Clinical Pharmacology and Toxicology, University Hospital Basel, Basel, Switzerland,2 Institute of Clinical Chemistry, University...
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Combination of Daptomycin plus Ceftriaxone Is More Active than Vancomycin plus Ceftriaxone in Experimental Men
Antimicrobial Agents and Chemotherapy, July 2009, p.3030-3033, Vol. 53, No. 7 Copyright 2009, American Society for Microbiology. All Rights Reserved. Egermann,1 Z. Stanga,1 A. Ramin,4 F. Acosta,1 A. Stucki,1 P. Gerber,2...
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The High Rate of Adverse Drug Events in Children Receiving Prolonged Outpatient Parenteral Antibiotic Therapy
Pediatric Infectious Disease Journal, 06/24/09 Print Save in My Library Free Abstract Faden BA et al.- Forty-five children treated with 82 courses of 15 different antibiotics over 344 weeks during outpatient parenteral antibiotic therapy...
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Skin And Skin Structure Infections Are The Second Most Common Diagnoses For Which An Antibiotic Is Used In The
Arlington Medical Resources (AMR), a provider of premier market intelligence for the pharmaceutical and diagnostic imaging industries, finds that for the July - December 2008 time period, skin and skin structure infections continue to be the...
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Skin and Skin Structure Infections Are the Second Most Common Diagnoses for Which an Antibiotic Is Used in the
Most of These Infections Are Treated Empirically While Just Under One-Third Are Documented Arlington Medical Resources Introduces a New Executive Dashboard for The Hospital Antibiotic Market Guide MALVERN, Pa., June 22 /PRNewswire/ --...
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Skin and Skin Structure Infections Are the Second Most Common Diagnoses for Which an Antibiotic Is Used in the
Most of These Infections Are Treated Empirically While Just Under One-Third Are Documented Arlington Medical Resources Introduces a New Executive Dashboard for The Hospital Antibiotic Market Guide MALVERN, Pa., June 22 /PRNewswire/ --...
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Skin and Skin Structure Infections Are the Second Most Common Diagnoses for Which an Antibiotic Is Used in the
Most of These Infections Are Treated Empirically While Just Under One-Third Are Documented Arlington Medical Resources Introduces a New Executive Dashboard for The Hospital Antibiotic Market Guide MALVERN, Pa., June 22 /PRNewswire/ --...
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Epidemiology: Research conducted at NHS Foundation Trust, Microbiology Department has updated our knowledge ab
Research conducted at NHS Foundation Trust, Microbiology Department has updated our knowledge about epidemiology Fresh data on epidemiology are presented in the report 'Methicillin-resistant Staphylococcus aureus bacteraemia and mortality in...
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Recurrent Clostridium difficile infection: A review of risk factors, treatments, and outcomes
(Click the title below to leave the MDLinx Network and go to the Journal's Website) Journal of Infection, 06/10/09 Print Save in My Library Free Abstract Johnson S et al.- Current guidelines recommend that the first recurrent episode be...
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Ceftobiprole: a novel cephalosporin with activity against Gram-positive and Gram-negative pathogens, including
(Click the title below to leave the MDLinx Network and go to the Journal's Website) International Journal of Antimicrobial Agents, 06/11/09 Print Save in My Library Free Abstract Barbour A et al.- The clinical cure rates were similar for...
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In vitro antibacterial activity of tigecycline against resistant Gram-negative bacilli and enterococci by time
George A.Pankey, a, , and Deborah S. Ashcrafta aInfectious Disease Research, Ochsner Clinic Foundation, New Orleans, LA 70121, USA This timekill study was performed with 65 genetically unique clinical isolates of Gram-negative bacilli...
DiagnosticMicrobiology and Infectious Disease:
Jun 10 2009 10:51PM
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sarA inactivation reduces vancomycin-intermediate and ciprofloxacin resistance expression by Staphylococcus au
_ sarA inactivation reduces vancomycin-intermediate and ciprofloxacin resistance expression by Staphylococcus au.
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Macrolide resistance in Streptococcus pyogenes: prevalence, resistance determinants, and emm types
The resistance profiles and mechanism of macrolide resistance were investigated in isolates of Streptococcus pneumoniae Resistance to ERY and CLI was 3.3% and 2.3% for S.pneumoniae The prevalence of macrolide resistance is low in...
DiagnosticMicrobiology and Infectious Disease:
Jun 10 2009 10:52PM
Matching: vancomycin
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The attributable clinical and economic burden of skin and skin structure infections in hospitalized patients:
Learning objective: At the conclusion of this learning activity, participants should be familiar with the modes of action, clinical indications, dosage regimens, and contraindications and cautions for several novel antibacterial agents for...
DiagnosticMicrobiology and Infectious Disease:
Jun 10 2009 10:51PM
Matching: vancomycin
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American Society for Microbiology honors Melissa B. Miller
Molecular Diagnostics Breaking News EUREKALERT Contact: Garth Hogan The 2009 American Society for Microbiology (ASM) Siemens Healthcare Diagnostics Young Investigator Award is being presented to Melissa B.Miller, Ph. D., D(ABMM),...
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