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Tenofovir and changes in renal function
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Effect of tenofovir disoproxil fumarate on risk of renal abnormality in HIV-1-infected children on antiretrovi
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AIDS Care Gap Between Wealthy And Developing Countries Risks Becoming A Chasm
AIDS leaders gathering in London today face the daunting challenge of implementing new World Health Organization (WHO) recommendations for earlier treatment with better AIDS drug cocktails at a time when donors are backing away from the promise of "universal...
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AIDS Care Gap Between Wealthy And Developing Countries Risks Becoming A Chasm
AIDS leaders gathering in London today face the daunting challenge of implementing new World Health Organization (WHO) recommendations for earlier treatment with better AIDS drug cocktails at a time when donors are backing away from the promise of 'universal...
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Understanding Tenofovir-Associated Renal Toxicity
Save time and stay informed.Our physician-editors offer you clinical perspectives on key research and news. Such toxicity does not appear to be completely reversible with withdrawal of the medication. Activate your free online account for full access to...
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FTC vs. 3TC Is There a Difference?
Save time and stay informed.Our physician-editors offer you clinical perspectives on key research and news. In a retrospective analysis of patients with virologic failure, tenofovir + 3TC was associated with higher rates of drug resistance than...
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Chronic Renal Failure in HIV-Infected Patients: Incidence and Risk Factors (ANRS CO3 Aquitaine Cohort, France)
17th CROI Conference on Retroviruses and Opportunistic Infections San Francisco CA February 16-19, 2010 Reported by Jules Levin CROI 2010 Feb 16-19 SF E Deti1, G Chene1,2, M-A Vandenhende2, C Cazanave2, S Geffard1, E Lazaro2, J Roger-Schmeltz2, M Bruyand1, F...
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5-Year Tenofovir Therapy Is Associated with Maintained HBV Response and Renal Toxicity in HIV/HBV Co-infected
17th CROI Conference on Retroviruses and Opportunistic Infections San Francisco CA February 16-19, 2010 Reported by Jules Levin CROI Feb 16-19 SF Theodora de Vries-Sluijs*1, J Reijnders1, B Hansen1, H Zaaijer2, J Prins2, M Schutten1, R de Man1, H Janssen1, and...
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Short-Term Raltegravir Monotherapy Does Not Predispose Patients to Develop RAL Resistance During Subsequent Co
17th CROI Conference on Retroviruses and Opportunistic Infections San Francisco CA February 16-19, 2010 Reported by Jules Levin CROI 2010 Feb 16-19 SF Michael D.Miller, Richard J.O. Barnard, Marc Witmer, Jing Zhao, Bach-Yen Nguyen, Hedy Teppler, and Daria...
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Stopping Tenofovir Doesnt Always Reverse Kidney Damage
Kidney damage caused by tenofovir (found in Viread, Truvada and Atripla) may not reverse itself after a year of discontinuing the drug, according to new study results published ahead of print on the website for the Journal of Acquired Immune Deficiency...
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Chronic Kidney Disease Linked to Tenofovir (Viread) in EuroSIDA Study
People with HIV have an elevated risk for kidney impairment compared with the general population, likely attributable to a combination of chronic viral infecti Chronic Kidney Disease Linked to Tenofovir (Viread) in EuroSIDA Study.
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Tenofovir-Related Renal Dysfunction Can't Always Be Reversed
Tenofovir nephrotoxicity can't always be fully reversed in HIV-infected men, acc Tenofovir-Related Renal Dysfunction Can't Always Be Reversed.
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Tenofovir-Related Renal Dysfunction Can't Always Be Reversed
_ Tenofovir-Related Renal Dysfunction Can't Always Be Reversed.
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Antiretrovirals For Prevention: tenofovir, FTC, maraviroc; rectal, vaginal, semen
17th CROI Conference on Retroviruses and Opportunistic Infections San Francisco CA February 16-19, 2010 Reported by Jules Levin CROI 2010 Feb 16-19 SF Efficacy of Intermittent Prophylaxis with Tenofovir and Emtricitabine against Rectal SHIV Transmission...
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The Kidney at CROI
17th CROI Conference on Retroviruses and Opportunistic Infections San Francisco CA February 16-19, 2010 Christina M.Wyatt, MD Assistant Professor, Medicine/ Nephrology Mount Sinai School of Medicine New York, NY Kidney disease and other non-AIDS...
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Chronic Kidney Disease and Exposure to ART in a Large Cohort with Long-term Follow-up: The EuroSIDA Study - ab
17th CROI Conference on Retroviruses and Opportunistic Infections San Francisco CA February 16-19, 2010 Reported by Jules Levin CROI Feb 16-19 2010 SF Ole Kirk*1, A Mocroft2, P Reiss3, S De Wit4, D Sedlacek5, M Beniowski6, J Gatell7, A Phillips2, B Ledergerber8...
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Abacavir (Ziagen) Does Not Compromise Effectiveness of Hepatitis C Treatment, but Zidovudine (Retrovir) May Re
The effect of accompanying antiretroviral drugs on virological response to hepatitis C therapy using remains uncertain, given that prior studies have produced conflicting results.Like ribavirin, zidovudine can cause anemia, which may increase the risk of...
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Liver Toxicity in an International Cohort of HIV/HBV Coinfected Patients on Long-term Antiretroviral Therapy
HIV/HBV coinfection is associated with more rapid liver disease progression and increased risk for hepatotoxicity (liver toxicity) in patients receiving combination ART.ART can cause liver injury by a variety of mechanisms including direct drug toxicity,...
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Tenofovir-associated kidney problems not always reversible
Kidney function does not always return to normal after treatment with tenofovir is discontinued because of renal toxicities, Australian investigators report in an advance online publication in the Journal of Acquired Immune Deficiency Syndromes.An...
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Tenofovir Tied to Renal Problems in Children With HIV
Prolonged use of tenofovir by children with HIV infection is linked with hypopho Tenofovir Tied to Renal Problems in Children With HIV.
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Tenofovir Tied to Renal Problems in Children With HIV
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The Future of First-Line HIV Treatment: Are Atripla's Days as King Numbered?
A Blog Entry From CROI 2010 Atripla (which is a combination of efavirenz + tenofovir + emtricitabine) is the acknowledged king in the realm of first-line antiretroviral therapy.long_space Le Roi est mort, vive le Roi!long_space Not so fast: The king still...
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Elvucitabine Versus 3TC in First-Line Regimens for 96 Weeks - see slides from poster below
17th CROI Conference on Retroviruses and Opportunistic Infections San Francisco CA February 16-19, 2010 17th Conference on Retroviruses and Opportunistic Infections, February 16-19, 2010, San Francisco Mark Mascolini Elvucitabine, a cytosine nucleoside analog,...
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Cayston Nod a Small Win for Gilead Ahead of New HIV Data
Gilead Sciences Inc.'s ongoing strategy to diversify its pipeline scored a small victory with the approval of inhaled aztreonam lysine drug Cayston, but there's no question the firm's future growth still hinges largely on its next-generation HIV pipeline.
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Bone Fractures at CROI 2010 - see slides below
17th CROI Conference on Retroviruses and Opportunistic Infections San Francisco CA February 16-19, 2010 Reported by Jules Levin In the summer of 2009 a research group from Boston including Steve Grinspoon published the first large study paper showing increased...
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