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More Than A Supplier
Being a custom manufacturer of active pharmaceutical ingredients (APIs) for drug company customers can be rewarding on its own, but there is more to be gained financially by making and selling the final drug.

As a rule of thumb, suppliers know that the API...

Chemical & Engineering News:  Mar 16 2010 4:51AM
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Pfizer's 3 Points of Failure
Pfizer (NYSE: PFE) is not having a good March.

Last week, its Cinderella story, Alzheimer's drug Dimebon, which it licensed from Medivation (Nasdaq: MDVN), failed its first phase 3 trial for effectiveness.

And then yesterday, the clinical-trial (March)...

Motley Fool via MSN Money:  Mar 12 2010 8:02PM
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Better living through green chemistry: Pharmaceuticals
Magazine issue 2751.

Subscribe and get 4 free issues.

Most purchases of sildenafil citrate - the generic name of Viagra - are not motivated by urges of an environmental kind.

But this blockbuster drug has long been a poster-child for its manufacturer...

New Scientist:  Mar 12 2010 7:12PM
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Genetic Test Could Be Used To 'Personalise' Drugs, Say Scientists
The test should allow doctors to prescribe drugs only to those people who are likely to benefit from the medicines rather than giving them - and their side-effects- to a wide range of patients in the knowledge that only some individuals will respond to the...
Nigeria Guardian:  Mar 6 2010 4:00PM
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Gene Test Hope For Personalised Breast Cancer Treatment
Cancer Research UK scientists have developed a system to identify faulty or missing genes that could prevent specific chemotherapy regimes from working.

This opens the doors for targeted breast cancer treatment, according to research published in the Lancet...

Medical News Today:  Mar 2 2010 3:28PM
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Can genes predict drug response?
Researchers have identified 'a genetic signature that can determine whether breast cancer is likely to respond to a common treatment', The Times reported.

It said researchers had found that measuring the activity of six genes could forecast whether a breast...

Nursing Times:  Mar 2 2010 2:37PM
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Gene research offers new hope for targeted breast cancer treatment
CANCER RESEARCH UK scientists have developed a system to identify faulty or missing genes that could prevent specific chemotherapy regimes from working.

This opens the doors for targeted breast cancer treatment, according to research published in the Lancet...

News-Medical.Net:  Mar 2 2010 6:04AM
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Gene test hope for personalised breast cancer treatment
CANCER RESEARCH UK scientists have developed a system to identify faulty or missing genes that could prevent specific chemotherapy regimes from working.

This opens the doors for targeted breast cancer treatment, according to research published in the Lancet...

Health Canal:  Mar 2 2010 5:09AM
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New gene test could hold key to chemotherapy receptiveness
A new gene test investigated by scientists is said to be able to predict how well a cancer patient with respond to chemotherapy.

It is hoped the new test could mean patients do not have to undertake unnecessary treatment as it will determine whether they are...

In The News.co.uk:  Mar 1 2010 12:47PM
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Can genes predict drug response?
<div><p><p>Researchers have identified a genetic signature that can determine whether breast cancer is likely to respond to a common treatment,<em> The Times</em> reported.

It said researchers had found that measuring the...

National Library for Health NHS:  Mar 1 2010 11:12PM
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Can genes predict drug response?
Genetic tests may help to personalise treatment Researchers have identified a genetic signature that can determine whether breast cancer is likely to respond to a common treatment, The Times reported.

It said researchers had found that measuring the activity...

NHS Choices:  Mar 1 2010 10:13PM
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Gene test hope for personalised breast cancer treatment
CANCER RESEARCH UK scientists have developed a system to identify faulty or missing genes that could prevent specific chemotherapy regimes from working.

This opens the doors for targeted breast cancer treatment, according to research published in the Lancet...

Cancer Research UK:  Mar 1 2010 9:10PM
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Genetic test could be used to 'personalise' drugs, say scientists
Scientists are developing a genetic test that may tell the difference between cancer patients who are likely to respond to treatment with a powerful anti-tumour drug and those people for whom the drug will be useless.

The test should allow doctors to...

The Independent:  Mar 1 2010 12:20AM
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Gene test could prevent ineffective use of Taxol in breast cancer
A genetic signature that can determine whether breast cancer is likely to respond to a common treatment has been identified, promising more personalised care for patients.

The advance by British scientists could allow doctors to predict which types of...

Times Online:  Feb 28 2010 9:28PM
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Gene test could personalise cancer care
A genetic signature that can determine whether breast cancer is likely to respond to a common treatment has been identified, promising more personalised care for patients.

The advance by British scientists could allow doctors to predict which types of...

Times Online:  Feb 28 2010 9:03PM
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Lorus Announces Publication Demonstrating Antitumor Efficacy of Interleukin 17E
TORONTO, ONTARIO--(Marketwire - Feb.

24, 2010) - Lorus Therapeutics Inc.

(TSX:LOR)('Lorus'), a biopharmaceutical company specializing in the research and development of pharmaceutical products and technologies for the management of cancer, today announced a...

Therapeutics Daily:  Feb 24 2010 2:49PM
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Lorus Announces Publication Demonstrating Antitumor Efficacy of Interleukin 17E
Lorus Therapeutics Inc.

(TSX: LOR)('Lorus'), a biopharmaceutical company specializing in the research and development of pharmaceutical products and technologies for the management of cancer, today announced a publication demonstrating the antitumor activity...

Genetic Engineering News:  Feb 24 2010 1:53PM
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Lorus Announces Publication Demonstrating Antitumor Efficacy of Interleukin 17E Potent anticancer activity against several common tumor types
(Marketwire via COMTEX News Network) -- Lorus Therapeutics Inc.

(TSX:LOR)("Lorus"), a biopharmaceutical company specializing in the research and development of pharmaceutical products and technologies for the management of cancer, today announced a...

Quote.com Canada:  Feb 24 2010 1:25PM
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A Flow Cytometry Method to Quantitate Internalized Immunotoxins Shows that Taxol Synergistically Increases Cellular Immunotoxins Uptake
Zhang Y et al.

The findings offer a mechanistic rationale to combine SS1P with Taxol or another cytotoxic drug as a strategy to increase immunotoxin uptake by tumor cells.

A Flow Cytometry Method to Quantitate Internalized Immunotoxins Shows that ...

MDLinx:  Feb 23 2010 9:36AM
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Distribution of kinetochore fragments during mitosis with unreplicated genomes
When hydroxyurea and caffeine are added to Chinese hamster ovary cells, the cells bypass the S-phase checkpoint, and enter unscheduled mitosis.

These cells build a morphologically normal spindle, and distribute unreplicated kinetochore fragments to daughters....

Journal of Cytoskeleton:  Feb 20 2010 8:01AM
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Uspto Grants Formatech Novel Drug Formulation Patent
Recently, Formatech, Inc.

announced the issuance of U.S.

patent 7,659,310, entitled "Methods of Enhancing Solubility of Agents" which covers novel formulation methods to enhance the solubility of certain hydrophobic compounds.

The patented nanoparticle...

Pharmaceutical Online:  Feb 15 2010 11:05AM
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CRO NexMed raises $2.7m to develop delivery tech
CRO NexMed has received a $2.7m (2.0m) cash boost, which improves its financial situation and provides funds to develop its NexACT technology for oral and transdermal delivery.

On September 30 NexMed had $1.5m in cash and had lost compliance with NASDAQ.

Outsourcing Pharma:  Feb 13 2010 2:40AM
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Biopharmaceutical Winners: CVM, NEXM, OPXA - sourced PicksThatMove.com
CEL-SCI Corporation, NexMed, Inc., Opexa Therapeutics Inc.

Calgary, AB 2/12/2010 09:59 PM GMT (TransWorldNews) Calgary, Alberta - PicksThatMove.com opines promising trading opportunities with likely potential for gain.

The companies we follow have...

TransWorldNews:  Feb 12 2010 10:21PM
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Formatech issued patent covering novel formulation methods to enhance solubility of certain hydrophobic compounds
Today, Formatech, Inc.

announced the issuance of U.S.

patent 7,659,310, entitled Methods of Enhancing Solubility of Agents which covers novel formulation methods to enhance the solubility of certain hydrophobic compounds.

The formulation technology is...

News-Medical.Net:  Feb 12 2010 9:42AM
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New ovarian cancer drug tested
The University of Kansas Cancer Center began running a Phase I clinical trial of the anti-ovarian cancer drug Nanotax.

Nanotax is a breakthrough drug because, unlike other anti-cancer drugs, it is water-soluble.

Charles Decedue, Valentino Stella, Bala...

University Daily Kansan:  Feb 12 2010 3:06AM
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