Transgenic wheat has increased polyamines Crop productivity relies heavily on abundant supplies of water for irrigation.Although drought and salt tolerance genes are present in wheat, breeding for stress tolerance is time- and labour-intensive and complicated by the multigenic...
Hot paper in Gene Expression: Caution: RNAi Biophoto Associates / Photo Researchers, Inc.Grimm et al., 'Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways,' Nature, 441:537-41, 2006.
(Cited in 147 papers) While studying the potential of RNA...
Calcium Deposits and Heart Disease Prof.Joe Cumminsspeaks on a health issue closest to his heart Public education versus personal case notes The Framingham health study has been following the health of residents in the Massachusetts town in the United States since 1948 and...
TopAbstracts in Alzheimer's 06/26/2008 TopAbstracts in Alzheimer's are the abstracts most highly rated/most read by nearly 300,000 physicians who received a Doctor's Guide newsletter or visited a website Powered by Doctor's Guide in the past 14 days.Over 2000 peer-reviewed...
Handle with care Last Autumn, I stowed away at the UK's Primary Care Diabetes Society conference.I wanted to know more about the disease that, according to the 2002 report by Sir Derek Wanless, threatens to bankrupt the UK's National Health Service (NHS)...
Mice Expressing Human Genes Bred to Help Unravel Mental Disorders New mouse strains engineered to express human genes related to mental disorders are being developed under a recently-launched grant program from NIMHs Division of Neuroscience and Basic Behavioral Science.The new models are designed to...
Immune-Based Therapy With Glatiramer Acetate for Dry AMD GENNADY LANDA, MD OLEG BUTOVSKY, PhD JOHAI SHOSHANI, MD MICHAL SCHWARTZ, PhD AYALA POLLACK, MD Age-related macular degeneration (AMD) and Alzheimer's disease (AD) are chronic neurodegenerative diseases that are strongly associated with...
Soliris(R) Improved Fatigue Independent of Changes in Anemia in Patients with PNH by Controlling Hemolysis Data Suggest Role of Hemolysis in PNH-Related Fatigue CHESHIRE, Conn., June 15 /PRNewswire-FirstCall/ -- Soliris(R) (eculizumab) therapy improved the often disabling fatigue experienced by patients with the rare blood disorder paroxysmal...
Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes Background In patients with type 2 diabetes, the effects of intensive glucose control on vascular outcomes remain uncertain.Methods We randomly assigned 11,140 patients with type 2 diabetes to undergo either standard glucose control or...
Reframing ADHD in the Genomic Era The Emerging View of ADHD in the 21st Century: More Complex Than Previously Believed.In the era of genomics, psychiatrylike all areas of medicinewill likely undergo radical change.
As genetic risk factors are uncovered and the dynamic...
Frontiers in Psychiatric Research Dr Wong is Miller Professor and vice-chair for translational research and Dr Arcos-Burgos is research associate professor in the department of psychiatry and behavioral sciences at the Leonard M.Miller School of Medicine, University of...
Effects of Intensive Glucose Lowering in Type 2 Diabetes The Action to Control Cardiovascular Risk in Diabetes Study Group ABSTRACT Background Epidemiologic studies have shown a relationship between glycated hemoglobin levels and cardiovascular events in patients with type 2 diabetes.We...
Lipoxygenase identified as possible target for asthma therapy Am J Respir Cell Mol Biol 2008; Advance online publication MedWire News: Mice deficient in 15-lipoxygenase (LO)-1 do not establish fully developed allergic airway inflammation despite having fully developed systemic sensitization,...
Airway inflammation induced by NTHi exposure Am J Respir Cell Mol Biol 2008; 38: 629-638 MedWire News: Aspects of chronic obstructive pulmonary disease (COPD) can be induced by repetitive exposure to nontypeable Haemophilus influenzae (NTHi), according to US researchers.The...
The Opioid System and Antidepressant Response: How the Opioid System Affects Response to Psychophary The -Opioid System and Antidepressant Response How the Opioid System Affects Response to Psychopharmacology This article discusses the role of -opioid receptors (MORs) in antidepressant treatment and major depressive disorder (MDD).
New Positive Data Announced for NKTR-102 (PEG-irinotecan), Highlights Promise of Nektar's Innovative Small Mol SAN CARLOS, Calif., June 2 /PRNewswire-FirstCall/ -- Nektar Therapeutics announced new positive data today from a Phase 1 clinical study for NKTR-102 (PEG-irinotecan) in advanced cancer patients whose tumors had progressed on other therapies...
New Positive Data Announced for NKTR-102 (PEG-irinotecan), Highlights Promise of Nektar's Innovative Small Mol /PRNewswire-FirstCall/ -- Nektar Therapeutics announced new positive data today from a Phase 1 clinical study for NKTR-102 (PEG-irinotecan) in advanced cancer patients whose tumors had progressed on other therapies.Significant anti-tumor...
New Positive Data Announced for NKTR-102 (PEG-irinotecan), Highlights Promise of Nektar's Innovative Small Mol SAN CARLOS, Calif., June 2 /PRNewswire-FirstCall/ -- Nektar Therapeutics announced new positive data today from a Phase 1 clinical study for NKTR-102 (PEG-irinotecan) in advanced cancer patients whose tumors had progressed on other therapies...
New Positive Data Announced for NKTR-102 (PEG-irinotecan), Highlights Promise of Nektar's Innovative Small Mol SAN CARLOS, Calif., June 2 /PRNewswire-FirstCall/ -- Nektar Therapeutics (Nasdaq: NKTR) announced new positive data today from a Phase 1 clinical study for NKTR-102 (PEG-irinotecan) in advanced cancer patients whose tumors had progressed on...
Diabetes treatments: from supplements to foods New research findings into traditional supplemental ingredients are driving new applications for diabetes health.Food formulators are taking note, and incorporating GRAS-approved ingredients into their offerings, and also utilising better...
New Data Offers Insights Into the Potential Role for TYKERB(R) /PRNewswire-FirstCall via COMTEX/ -- GlaxoSmithKline today announced the results of three studies evaluating TYKERB -- an oral, small molecule inhibitor of HER2 -- in various breast cancer settings, either in combination with other targeted...
New Data Offers Insights Into the Potential Role for TYKERB(R) (Lapatinib) in Non-Cytotoxic Chemotherapy-Based LONDON, and PHILADELPHIA, June 1 /PRNewswire-FirstCall/ -- GlaxoSmithKline today announced the results of three studies evaluating TYKERB -- an oral, small molecule inhibitor of HER2 -- in various breast cancer settings, either in...
New Data Offers Insights Into the Potential Role for TYKERB(R) (Lapatinib) in Non-Cytotoxic Chemotherapy-Based LONDON, and PHILADELPHIA, June 1 /PRNewswire-FirstCall/ -- GlaxoSmithKline today announced the results of three studies evaluating TYKERB -- an oral, small molecule inhibitor of HER2 -- in various breast cancer settings, either in...
New Data Offers Insights Into the Potential Role for TYKERB(R) (Lapatinib) in Non-Cytotoxic Chemotherapy-Based LONDON, and PHILADELPHIA, June 1 /PRNewswire-FirstCall/ -- GlaxoSmithKline today announced the results of three studies evaluating TYKERB -- an oral, small molecule inhibitor of HER2 -- in various breast cancer settings, either in...
Research and Markets: Cytokinetics is the First Company to Systematically Investigate the Cytoskeleton and Mol - Research and Markets (http://www.researchandmarkets.com/reports/c93056) has announced the addition of 'Cytokinetics Inc: Premium Company Profile' to their offering.Cytokinetics is the first company to systematically investigate the...
