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Comparative Activity of TR-700 (Torezolid) Against Staphylococcal Blood Isolates Collected in Spain [Article]
The in vitro activity of TR-700 (torezolid) was evaluated against a collection of 660 staphylococcal blood isolates.TR-700 showed excellent activity against all the staphylococci tested. The MIC 50 /MIC 90 values of TR-700, linezolid, daptomycin, and...
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Comparative in vitro Antimicrobial Activity of Torezolid (TR-700), the Active Moiety of a New Oxazolidinone, Torezolid Phosphate (TR-701), Determination of Tentative Disk Diffusion Interpretive Criteria, and Quality Control Ranges [Article]
Comparative in vitro Antimicrobial Activity of Torezolid (TR-700), the Active Moiety of a New Oxazolidinone, Torezolid Phosphate (TR-701), Determination of Tentative Disk Diffusion Interpretive Criteria, and Quality Control Ranges Steven D.Brown* and Maria M...
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Activity of Linezolid in an In Vitro Pharmacokinetic-Pharmacodynamic Model Using Different Dosages and Staphyl
Activity of Linezolid in an In Vitro Pharmacokinetic-Pharmacodynamic Model Using Different Dosages and Staphylococcus aureus and Enterococcus faecalis Strains w Activity of Linezolid in an In Vitro Pharmacokinetic-Pharmacodynamic Model Using...
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Linezolid-Induced Thrombocytopenia
A 70-year-old male was admitted for treatment of an automatic implantable cardioverter defibrillator pocket cellulitis refractory to outpatient treatment.Intravenous antibiotics were started in the hospital while awaiting blood and pocket aspiration cultures...
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Pfizer grants MSU researcher $100K
Apoorv Kalra only has been a part of MSUs Division of Infectious Disease team for about a year and a half, and hes already living up to the MSU goal of advancing knowledge, officials said.Kalra, an assistant professor in MSUs College of Human Medicine, was...
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Pfizer honors MSU professor for work with staph bacteria
EAST LANSING, Mich.- An MSU assistant professor in the Department of Medicine is one of nine investigators nationwide to receive Pfizer's 2009 Young Investigator Antibacterial Research Awards. (Media-Newswire.com) - EAST LANSING, Mich. An MSU assistant...
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Comparative in vitro Antimicrobial Activity of Torezolid (TR-700), the Active Moiety of a New Oxazolidinone, T
Steven D.Brown* and Maria M. Traczewski The Clinical Microbiology Institute, 9725 SW Commerce Circle, Wilsonville, OR 97070 * To whom correspondence should be addressed. Email: SBrown{at}clinmicroinst.com. This study assessed the spectrum of activity...
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Clinical efficacy and tolerability of linezolid in pediatric patients: A systematic review
Critical Care Medicine, 03/01/10 Relevance Score: 91% Emergency Radiology, 02/04/10 Relevance Score: 91% Cancer Treatment Reviews, 03/05/10 Relevance Score: 90% Clinical efficacy and tolerability of linezolid in pediatric patients: A systematic review.<...
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A pill in time
Much like the proverb, 'A stitch in time saves nine', adhering to the prescribed dosage schedule is an important part of any treatment because missing a dose will only aggravate the disease.Pharmaceutical companies are therefore simplifying dosage schedules...
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Data from Boston Health Economics, Inc. provide new insights into antibiotics
Current study results from the report, 'Inpatient treatment patterns, outcomes, and costs of skin and skin structure infections because of Staphylococcus aureus,' have been published.'Staphylococcus aureus (SA) is a common bacterial pathogen in skin and skin...
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Antibiotics: Data from Boston Health Economics, Inc. provide new insights into antibiotics
Today's Medical & Research News Antibiotics Data from Boston Health Economics, Inc.provide new insights into antibiotics February 23rd, 2010 Printer-Friendly Version City:Waltham State:MA Country:United States Antibiotics Anti-Infectives Antibacterial...
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Resistance to Linezolid in a Porcine Clostridium perfringens Strain Carrying a Mutation in the rplD Gene Encod
Antimicrobial Agents and Chemotherapy, March 2010, p.1351-1353, Vol. 54, No. 3 Copyright 2010, American Society for Microbiology. All Rights Reserved. Resistance to Linezolid in a Porcine Clostridium perfringens Strain Carrying a Mutation in...
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Drug Resistance: Findings in drug resistance reported from Johnson & Johnson
Today's Medical & Research News Drug Resistance Findings in drug resistance reported from Johnson & Johnson February 22nd, 2010 Printer-Friendly Version City:Raritan State:NJ Country:United States Anti-Infectives Antimicrobial Resistance Antimicrobials...
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Findings in drug resistance reported from Johnson & Johnson
'Ceftobiprole, a broad-spectrum cephalosporin with activity against methicillin-resistant Staphylococcus aureus (MRSA) (P.Hebeisen et al., Antimicrob. Agents Chemother. 45: 825-836, 2001), was evaluated in a subcutaneous skin infection model with...
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Resistance to Linezolid in a Porcine Clostridium perfringens Strain Carrying a Mutation in the rplD Gene Encod
Antimicrobial Agents and Chemotherapy, March 2010, p.1351-1353, Vol. 54, No. 3 Copyright 2010, American Society for Microbiology. All Rights Reserved. Christina S. Hlzel,* Katrin S. Harms, Karin Schwaiger, and Johann Bauer Chair of Animal Hygiene...
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Pharmacokinetics of linezolid in septic patients with and without extended dialysis
Swoboda S et al.The results suggest that linezolid pharmacokinetics in critically ill patients with ARF undergoing ED is not comparable to that in healthy subjects and patients without ARF. Pharmacokinetics of linezolid in septic patients with...
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Pharmacodynamics - Study findings on pharmacodynamics are outlined in reports from University of Florida, Depa
Learn more about a six-week, no-risk free trial of Medical Letter on the CDC & FDA We're a pay-per-view site for premium content.If you'd like to purchase this article, it's only $3.00. Study findings on pharmacodynamics are outlined in reports...
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Antimicrobial susceptibility of multidrug-resistant Streptococcus pneumoniae strains with penicillin MICs of 8
Violeta Rodrguez-Cerrato, a, , , Matilde Graciaa, Gema del Pradoa, Lorena Huelvesa, Plnio Navesa, Vicente Ruiza, Carmen Pontea and Francisco Sorianoa a Department of Medical Microbiology and Antimicrobial Chemotherapy, Fundacin Jimnez Daz-Capio, 28040 Madrid,...
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Cempra completes enrolment in phase 2 portion of phase 2/3 trial of TAKSTA to treat skin infections
Cempra Pharmaceuticals announced completion of enrolment of the phase 2 portion of its phase 2/3 clinical trial of TAKSTA (sodium fusidate; CEM-102) for the treatment of acute bacterial skin and skin structure infections.The phase 2/3 trial uses an adaptive...
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Cempra Completes Enrollment of Phase 2 Portion of Phase 2/3 Clinical Trial of TAKSTA(TM) (CEM-102 or Sodium Fu
-- Clinical Program Expected to Rapidly Progress to Stage 2 (Phase 3) Portion of Clinical Study CHAPEL HILL, N.C., Jan.19 /PRNewswire/ -- Cempra Pharmaceuticals today announced completion of enrollment of the Phase 2 portion of its Phase 2/3 clinical trial...
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Cempra Completes Enrollment In Phase 2 Taksta Trial
Cempra Pharmaceuticals (Cempra) has completed enrollment in the phase 2 portion of its phase 2/3 clinical trial of Taksta, for the treatment of acute bacterial skin and skin structure infections.The phase 2/3 trial uses an adaptive-design in which the phase...
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