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Absence of placental growth factor blocks dextran sodium sulfate-induced colonic mucosal angiogenesis, increases mucosal hypoxia and aggravates acute colonic injury
Laboratory Investigation advance online publication, February 8, 2010.

doi:10.1038/labinvest.2010.

Absence of placental growth factor blocks dextran sodium sulfate-induced colonic mucosal angiogenesis, increases mucosal hypoxia and aggravates acute...

Laboratory Investigation: Feb 8 2010 8:03PM
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Reports summarize colitis animal studies study results from University of Munster
Scientists discuss in 'Insulin-like growth factor 1-coated sutures improve anastomotic healing in an experimental model of colitis' new findings in colitis.

'Exogenously applied insulin-like growth factor (rhIGF-1) may improve normal intestinal healing.

Poten & Partners: Feb 8 2010 5:51AM
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Dynamic monitoring of NET activity in mature murine sympathetic terminals using a fluorescent substrate
Background and purpose: To validate a fluorescence approach for monitoring norepinephrine transporter (NET) transport rate in mature sympathetic terminals, and to determine how prejunctional muscarinic receptors affect NET rate.Experimental approach: Confocal...

British Journal of Pharmacology: Feb 6 2010 1:43AM
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Iron Safety Hits AMAG Pharmaceuticals
Shares of AMAG Pharmaceuticals, Inc.

(AMAG) traded as low as $37.70 today, down nearly 17% from the prior close of $45.25 due to purported safety concerns regarding Feraheme [ferumoxytol], the companys marketed product for the treatment of iron...

Seeking Alpha: Feb 4 2010 10:34PM
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Factor VIII polymer conjugates
The invention is a proteinaceous construct comprising a Factor VIII molecule which is conjugated to a water-soluble polymer via carbohydrate moieties of Factor VIII, and methods of preparing same.

Description of the Invention SUMMARY OF THE INVENTION The...

PharmCast: Jan 27 2010 5:41AM
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Iron Therapy Reduces Hospital Stay in Colorectal Cancer Surgery Patients: Presented at ASCO-GI
-- Patients who undergo surgery for colorectal cancer and receive intravenous iron to correct low haemoglobin levels rather than packed red blood cells appear to have a significantly reduced hospital length of stay, researchers said here at the 2010...

Doctors Guide: Jan 25 2010 9:11PM
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Research on eye research detailed by scientists at University of Cincinnati
- (Rx.com) 'Electrically assisted delivery is noninvasive and has been investigated in a number of ocular drug delivery studies (see also Eye Research).

The objectives of this study were to examine the feasibility of electrically assisted delivery of...

Pharmacy Choice: Jan 25 2010 12:15PM
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FDA Pipeline preview, January 2010 (Testosterone undecanoate injection, Telavancin, Ampligen, Doxepin, Everolimus, Aztreonam lysine, Erlotinib, TG4010, BSI-201, Midazolam, Aimspro, Motorgraft, BHR-100, Dextran sulfate)
Complete response?

Extended-duration testosterone undecanoate injection (Aveed, Endo Pharmaceuticals Holdings) for men diagnosed with low testosterone?

Telavancin (Vibativ, Theravance) for the treatment of nosocomial pneumonia?

Biological response...

Modern Medicine: Jan 20 2010 4:26PM
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Dextran based pH-activated near-infrared fluorescence nanoprobe imaging the acidic compartments in cancer cells
Cong Li, Kai Li, Huihui Yan, Guanghui Li, Jinsong Xia, Xunbin Wei (Communication from Chem.

Commun.) Cong Li, Chem.

Commun., 2010, DOI: 10.

Dextran based pH-activated near-infrared fluorescence nanoprobe imaging the acidic compartments in cancer...

RSC: Jan 11 2010 11:38AM
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