Are all antipsychotics equal? Authors' reply
Jan Volavka suggests that we downplayed the superior effectiveness of the second-generation antipsychotics tested in our study compared with haloperidol. Our primary hypothesis (ie, all-cause discontinuation of a low dose of ...
Are all antipsychotics equal?
In the EUFEST study (March 29, p 1085),1 Ren Kahn and colleagues found that haloperidol, compared with several second-generation antipsychotics, was associated with higher rates of overall treatment discontinuation and discontinuation...
Government Report Finds Deficiencies in US Nursing Homes
Serious gaps in the quality of care of nursing home patients are missed or minimized by state inspectors, according to a May Government Accountability Office report.Among findings, the report found that state inspectors had missed at...
Nicotine Dependence in Schizophrenia: Prevalence, Mechanisms, and Implications for Treatment
Each year more than 440,000 people in the United States die of smoking-related illness, and nearly half a billion dollars in health-related economic losses are directly attributable to smoking.1,2 Cigarette smoking has been the single...
Rx Product News: Profile: A Closer Look at New FDA Actions: Nuvigil
Armodafinil (Nuvigil), a new wakeful-ness-promoting agent, received FDA approval on June 15, 2007.1 Nuvigil is indicated for patients experiencing obstructive sleep apnea/hypopnea syndrome (OSA/HS), narcolepsy, and shift work sleep disorder ...
Beware antipsychotic drugs in dementia
Dementia is often associated with challenging behavior, such as aggression and agitation.Antipsychotic drugs may be used to control this, but at some cost the person with dementia.
A new study shows that older people with dementia...
FDA demands new warnings for older antipsychotics
The US Food and Drug Administration has issued an alert requiring the manufacturers of conventional antipsychotic drugs to add a boxed warning to the drugs label which provides information about the risk of mortality in elderly patients...
FDA warns schizophrenia drugs pose fatal risk to some seniors
WASHINGTON (AP) - The government is warning doctors that prescribing a certain group of psychiatric drugs to seniors suffering from dementia can increase their risk of death.Anti-psychotic drugs are approved to treat schizophrenia and...
FDA warns schizophrenia drugs pose fatal risk to some seniors
FDA warns schizophrenia drugs pose fatal risk to some seniors Last Update: 6:45 pm (/File) WASHINGTON (AP) - The government is warning doctors that prescribing a certain group of psychiatric drugs to seniors suffering from dementia can...
FDA warns schizophrenia drugs pose fatal risk to some seniors
Conventional Antipsychotic Drugs Atypical Antipsychotics Compazine (prochlorperazine) Abilify (aripiprazole) Haldol (haloperidol) Clozaril (clozapine) Loxitane (loxapine) FazaClo (clozapine) Mellaril (thioridazine) Geodon (ziprasidone)...
Boxed Mortality Warning Added to Older Antipsychotics Given to Elderly Demented
Interview with: Thomas Laughren, M.D., FDA Center for Drug Evaluation & Research ROCKVILLE, Md., June 16 -- Old-line neuroleptic drugs have been given a boxed warning on an increased risk of death when used off-label in elderly patients...
TopAbstracts in Schizophrenia 06/12/2008
TopAbstracts in Schizophrenia are the abstracts most highly rated/most read by nearly 300,000 physicians who received a Doctor's Guide newsletter or visited a website Powered by Doctor's Guide in the past 14 days.Over 2000 peer-reviewed...
CYP2D6 Genotyping Predicts Response to Tamoxifen
SAN ANTONIO-Tamoxifen is highly effective in reducing the recurrence of breast cancer in the adjuvant setting and as palliative treatment in the metastatic setting, but not all women benefit from tamoxifen.Resistance to the beneficial...
Medications and Quality of Life With Schizophrenia
Dr Voruganti is associate professor of psychiatry and behavioral neurosciences at McMaster University in Hamilton, Ontario.He reports that he has received unrestricted research grants from AstraZeneca, Janssen, Lilly, and Novartis.
The...
Atypical Antipsychotics for Treatment of Schizophrenia Spectrum Disorders
Dr Cullen is an instructor in the division of child and adolescent psychiatry and a postdoctoral research fellow at the Center for Neurobehavioral Development; Dr Kumra is chair of the division of child and adolescent psychiatry; Mr Regan is...
Clinical Challenge
Herpes zoster occurs in 10% to 20% of the general population as a result of reactivation of the varicella-zoster virus (VZV) and is generally benign.It occurs more frequently in persons with cellular immunodeficiency and older age.
The...
Data Presented at the American Psychiatric Association (APA) Annual Meeting Demonstrate Iloperidone's Efficacy
/PRNewswire-FirstCall/ -- Data presented today on Vanda Pharmaceuticals Inc.'s investigational drug candidate, iloperidone, included its 4-week, short-term Phase III trial, as well as a pooled analysis of three long-term, 52-week trials,...