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Herpes Simplex Virus: Data on herpes simplex virus discussed by researchers at University of Illinois, Department of Pathology
Today's Medical & Research News Data on discussed by researchers at University of Illinois, Department of Pathology March 19th, 2010 Printer-Friendly Version City:Chicago State:Illinois Country:United States Angiology Endothelium HSV-1 Herpes Simplex Herpes...
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Effects of Localized Neurotrophin Gene Expression on Spiral Ganglion Neuron Resprouting in the Deafened Cochle
_ Effects of Localized Neurotrophin Gene Expression on Spiral Ganglion Neuron Resprouting in the Deafened Cochle.
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Glutamate-induced internalization of Cav1.3 L-type Ca2+ channels protects retinal neurons against excitotoxicity
Glutamate-induced rise in the intracellular Ca2+ level is thought to be a major cause of excitotoxic cell death, but the mechanisms that control the Ca2+ overload are poorly understood.Using immunocytochemistry, electrophysiology and Ca2+ imaging, we show...
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Homeostatic regulation of M-current modulates synaptic integration in secretomotor, but not vasomotor, sympathetic neurons in the bullfrog
We compared how vasomotor C neurons and secretomotor B neurons integrated identical patterns of virtual synaptic activity using dynamic clamp, perforated-patch recordings from dissociated bullfrog sympathetic ganglion cells.The synaptic template...
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BrainsGate - Pharmaceuticals & Healthcare - Deals and Alliances Profile - new market report released
Refer to a friend 2010-03-10 22:37:16 - BrainsGate - Pharmaceuticals & Healthcare - Deals and Alliances Profile - a new market research report on companiesandmarkets.com BrainsGate - Pharmaceuticals & Healthcare - Deals and Alliances Profile is an...
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Life Sciences: Recent findings from Hiroshima University, Department of Otolaryngology highlight research in life sciences
Today's Medical & Research News Life Sciences Recent findings from Hiroshima University, Department of Otolaryngology highlight research in life sciences March 9th, 2010 Printer-Friendly Version Country:Japan Life Sciences Immunology Otolaryngology...
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Effects of Localized Neurotrophin Gene Expression on Spiral Ganglion Neuron Resprouting in the Deafened Cochlea
Molecular Therapy advance online publication, March 9, 2010.doi:10.1038/mt.2010. Effects of Localized Neurotrophin Gene Expression on Spiral Ganglion Neuron Resprouting in the Deafened Cochlea.
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Early sacral neuromodulation prevents urinary incontinence after complete spinal cord injury
Sievert KD et al.Future SCI investigations will be conducted to evaluate the potential benefits of even earlier SNM placement to progressively enhance pelvic organ functionality. This new approach may provide important clues required for assessing whether...
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Interaction of neurotrophin signaling with Bcl-2 localized to the mitochondria and endoplasmic reticulum on spiral ganglion neuron survival and neurite growth
Enhanced spiral ganglion neuron (SGN) survival and regeneration of peripheral axons following deafness will likely enhance the efficacy of cochlear implants.Overexpression of Bcl-2 prevents SGN death but inhibits neurite growth. Here we assessed the...
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Clinical mimicry: Fabry disease masquerading as lupus?
Drs Thomas and Kavitha Waggoner are residents in internal medicine at Seton Hall University and St Michael's Medical Center in Newark, New Jersey.Dr Guma is director of rheumatology and osteopathic director of medical education at St Michael's Medical Center...
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Life Sciences: AstraZeneca reports research in life sciences
Today's Medical & Research News Life Sciences AstraZeneca reports research in life sciences March 5th, 2010 Printer-Friendly Version Country:Sweden Life Sciences Physiology New research, 'Dynamic expression of the TRPM subgroup of ion channels in developing...
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Expression of synapsin and co-localization with serotonin and RFamide-like immunoreactivity in the nervous system of the chordoid larva of Symbion pandora (Cycliophora)
Abstract.Cycliophora is one of the most recently described metazoan phyla and hitherto includes only two species: Symbion pandora and Symbion americanus. With a very complex life cycle, cycliophorans are regarded as an enigmatic group with an uncertain...
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Role of Sphenopalatine Ganglion Neuroablation in the Management of Cluster Headache
Narouze SN Cluster headache is a primary neurovascular headache.It is a strictly unilateral head pain that is associated with cranial autonomic symptoms and usually follows circadian and circannual patterns. Chronic cluster headache, which accounts for...
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Biochemical and functional properties of distinct nicotinic acetylcholine receptors in the superior cervical ganglion of mice with targeted deletions of nAChR subunit genes
Nicotinic acetylcholine receptors (nAChRs) mediate fast synaptic transmission in ganglia of the autonomic nervous system.Here, we determined the subunit composition of hetero-pentameric nAChRs in the mouse superior cervical ganglion (SCG), the function...
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Quark Announces Dosing Of The First Patient In Phase I Clinical Trial Of Its Ocular Neuroprotective Agent, QPI-1007
QPI-1007 is Quark's First Drug Candidate to Utilize a Proprietary siRNA Fremont, CA/PRNewswire/ -- Quark Pharmaceuticals, Inc., a world leader in the discovery and development of RNAi-based therapeutics, announced today the dosing of the first patient in a...
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Quark Announces Dosing Of The First Patient In Phase I Clinical Trial Of Its Ocular Neuroprotective Agent, QPI
Quark Pharmaceuticals, Inc., a world leader in the discovery and development of RNAi-based therapeutics, announced the dosing of the first patient in a Phase I study of the investigational neuroprotective agent, QPI-1007.This drug candidate, having a...
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Quark Pharmaceuticals commences dosing in clinical study of QPI-1007 for NAION
Quark Pharmaceuticals, Inc., a world leader in the discovery and development of RNAi-based therapeutics, announced today the dosing of the first patient in a Phase I study of the investigational neuroprotective agent, QPI-1007.This drug candidate, having a...
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Chemical burns best treated with buffer, intraocular pressure spike prevention
San Francisco?When initially treating patients with acute chemical burns of the eye, Claes H.Dohlman, MD, PhD, advised use of a buffering solution for irrigation rather than isotonic saline, which is ineffective according to German investigators. Figure 1...
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Comparison of AAV Serotypes for Gene Delivery to Dorsal Root Ganglion Neurons
Molecular Therapy advance online publication, February 23, 2010.doi:10.1038/mt.2010. Comparison of AAV Serotypes for Gene Delivery to Dorsal Root Ganglion Neurons.
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Immunohistochemical Localization of SNARE Proteins in Dental Pulp and Periodontal Ligament of the Rat Incisor
Distribution of three soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor (SNARE) proteins, syntaxin-1, synaptosomal-associated protein of 25 kDa (SNAP-25), and vesicle-associated membrane protein-2 (VAMP-2), was examined in dental...
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Neuroprotection for treatment of glaucoma in adults
Sena DF et al.Glaucoma is a leading cause of blindness worldwide. It is classified as a group of conditions characterized by progressive damage to the optic nerve, deterioration of retinal ganglion cells and ultimately visual field loss. With...
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Researchers at University of Connecticut, Department of Neuroscience release new data on neuroscience
Data detailed in 'Inactivation of fibroblast growth factor receptor signaling in myelinating glial cells results in significant loss of adult spiral ganglion neurons accompanied by age-related hearing impairment' have been presented.'Hearing loss has...
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Neuroscience: Researchers at University of Connecticut, Department of Neuroscience release new data on neuroscience
Today's Medical & Research News Neuroscience Researchers at University of Connecticut, Department of Neuroscience release new data on neuroscience February 16th, 2010 Printer-Friendly Version City:Farmington State:Connecticut Country:United States Embryonic...
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Mouse with deficiency of glutamate transporter GLAST function
Mouse with deficiency of glutamate transporter GLAST United States Patent: 7,642,399 Issued: January 5, 2010 Inventors: Kohichi (Kanagawa, JP), Takayuki (Tokyo, JP) Assignee: Japan Science and Technology Agency (Saitama, JP) Appl.No.: 10/553,051 Filed: April...
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