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Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, M
Malignant melanomas are highly resistant to chemotherapy.

First-line chemotherapeutics used in melanoma therapy are the methylating agents dacarbazine (DTIC) and temozolomide (TMZ) and the chloroethylating agents BCNU and fotemustine...

Nature:  Jan 6 2009 11:30PM
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