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The neurology of coeliac disease in childhood: what is the evidence? A systematic review and meta-analysis
Aim The aim of this article was to review and conduct a meta-analysis of the paediatric literature on the neurology of coeliac disease.Method We conducted a review of paediatric studies published in English assessing neurological illness in coeliac disease...
Developmental Medicine and Child Neurology:  Mar 20 2010 4:22AM
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Alcoholism Prevention: Data on alcoholism prevention published by researchers at Stanford University
Today's Medical & Research News Alcoholism Prevention Data on alcoholism prevention published by researchers at Stanford University March 18th, 2010 Printer-Friendly Version City:Stanford State:California Country:United States Alcoholism Prevention...
NewsRX:  Mar 18 2010 4:17AM
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A new Purkinje cell antibody (anti-Ca) associated with subacute cerebellar ataxia: immunological characterization
Jarius S et al.

The authors report on a newly discovered serum and cerebrospinal fluid (CSF) reactivity to Purkinje cells (PCs) associated with subacute inflammatory cerebellar ataxia.

A new Purkinje cell antibody (anti-Ca) associated with subacute ...

MDLinx:  Mar 16 2010 11:11AM
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In vivo demonstration of microstructural brain pathology in progressive supranuclear palsy: A DTI study using TBSS
Knake S et al.

Significant increases in RD, a potential measure of altered myelin integrity, occurred bilaterally in the superior cerebellar peduncle, the cerebellar white matter, the vermis of the cerebellum, the fornix, the body of the corpus...

MDLinx:  Mar 15 2010 6:34AM
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Aneurysm Therapy: Research from Ege University, Department of Radiology has provided new data on aneurysm therapy
Today's Medical & Research News Aneurysm Therapy Research from Ege University, Department of Radiology has provided new data on aneurysm therapy March 14th, 2010 Printer-Friendly Version City:Izmir Country:Turkey Aneurysm Therapy Aneurysm Angiology Basilar...
NewsRX:  Mar 14 2010 5:04AM
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Reduced expression of the Ca2+ transporter protein PMCA2 slows Ca2+ dynamics in mouse cerebellar Purkinje neurones and alters the precision of motor coordination
Cerebellar Purkinje neurones (PNs) express high levels of the plasma membrane calcium ATPase, PMCA2, a transporter protein critical for the clearance of calcium from excitable cells.

Genetic deletion of one PMCA2 encoding gene in heterozygous PMCA2...

Journal of Physiology:  Mar 13 2010 8:09AM
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Basal ganglia hypoactivity during grip force in drug nave Parkinson's disease
The basal ganglia (BG) are impaired in Parkinson's disease (PD), but it remains unclear which nuclei are impaired during the performance of motor tasks in early-stage PD.

Therefore, this study was conducted to determine which nuclei function abnormally, and...

Human Brain Mapping:  Mar 12 2010 10:42AM
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In vivo demonstration of microstructural brain pathology in progressive supranuclear palsy: A DTI study using TBSS
We investigated DTI changes, potentially indicating alterations of microstructure and brain tissue integrity in 13 patients with probable progressive supranuclear palsy (PSP, Richardson syndrome) at stage III or less and 10 age-matched controls using a whole...
Movement Disorders:  Mar 11 2010 5:38PM
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Profile of Mary E. Hatten
Frederick P.

Rose Professor, Laboratory of Developmental Neurobiology, The Rockefeller University, New York, NY, USA Kristie Nybo, Ph.

Full Text (PDF) Mary Beth Hatten's role in developing methods for real-time imaging of neuronal migration and research on...

Bio Techniques:  Mar 10 2010 4:50AM
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An overview of L-2-hydroxyglutarate dehydrogenase gene (L2HGDH) variants: a genotype-phenotype study
L-2-Hydroxyglutaric aciduria (L2HGA) is a rare, neurometabolic disorder with an autosomal recessive mode of inheritance.

Affected individuals only have neurological manifestations, including psychomotor retardation, cerebellar ataxia, and more variably...

Human Mutation:  Mar 9 2010 1:03AM
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Differential involvement of the extracellular 6-O-endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity
The extracellular sulfatases Sulf1 and Sulf2 remove specific 6-O-sulfate groups from heparan sulfate, thereby modulating numerous signalling pathways underlying development and homeostasis.

In vitro data have suggested that the two enzymes show functional...

Journal of Cellular and Molecular Medicine:  Mar 5 2010 9:12AM
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Life Sciences: Study results from Hacettepe University, Institute of Oncology provide new insights into life sciences
Today's Medical & Research News Life Sciences Study results from Hacettepe University, Institute of Oncology provide new insights into life sciences March 4th, 2010 Printer-Friendly Version City:Ankara Country:Turkey Life Sciences Lhermitte-Duclos Disease...
NewsRX:  Mar 4 2010 5:03AM
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A Painful Pause
Dhillon AK et al.

An 83yearold man had lancinating throat pain, triggered by swallowing, coughing, and even speaking.

He would pass out with excruciating pain.

Magnetic resonance imaging showed an abnormal posterior inferior cerebellar artery loop ...

MDLinx:  Mar 2 2010 9:38AM
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Life Sciences: Studies from KAN Research Institute Inc. have provided new data on life sciences
Today's Medical & Research News Life Sciences Studies from KAN Research Institute Inc.

have provided new data on life sciences February 27th, 2010 Printer-Friendly Version City:Kobe Country:Japan Life Sciences Developmental Biology Cardiology New research...

NewsRX:  Feb 27 2010 5:22AM
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Adult peroxisomal acyl-coenzyme A oxidase deficiency with cerebellar and brainstem atrophy
_ Adult peroxisomal acyl-coenzyme A oxidase deficiency with cerebellar and brainstem atrophy.
Journal of Neurology, Neurosurgery & Psychiatry:  Feb 26 2010 4:44AM
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Reversible cerebellar toxicity during treatment with ornidazole: the first case report
_ Reversible cerebellar toxicity during treatment with ornidazole: the first case report.
Journal of Neurology, Neurosurgery & Psychiatry:  Feb 26 2010 4:44AM
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Lack of Mid1, the Mouse Ortholog of the Opitz Syndrome Gene, Causes Abnormal Development of the Anterior Cerebellar Vermis
_ Lack of Mid1, the Mouse Ortholog of the Opitz Syndrome Gene, Causes Abnormal Development of the Anterior Cerebellar Vermis.
Journal of Neuroscience:  Feb 25 2010 2:15AM
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Change in neuron aggregation and neurite fasciculation on EVAL membranes modified with different diamines
In this study, we modified poly(ethylene-co-vinyl alcohol) (EVAL) membranes by the covalent bonding of diamines via epoxidation of surface hydroxyl groups of EVAL to analyze the effect of immobilized diamines with different carbon chain length on the cultured ...
Journal of Biomedical Materials Research Part A:  Feb 23 2010 2:01AM
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Non-cerebellar primitive neuroectodermal tumors (PNET): Summary of the Milan consensus and state of the art workshop on marrow ablative chemotherapy with hematopoietic cell rescue for malignant brain tumors of childhood and adolescents
CNS non-cerebellar primitive neuroectodermal tumors (PNET) represent <5% of all childhood brain tumors.

Despite similar therapies, these patients have had significantly worse outcomes compared to patients with medulloblastoma.

Although these tumors...

Pediatric Blood and Cancer:  Feb 18 2010 1:07PM
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The Cerebellum in Children with Spina Bifida and Chiari II Malformation: Quantitative Volumetrics by Region
Juranek J et al.

Children with thoracic level lesions had smaller cerebellar volumes relative to those with lumbar/sacral lesions, who had smaller volumes compared to TD children.

The Cerebellum in Children with Spina Bifida and Chiari II Malformation...

MDLinx:  Feb 18 2010 9:28AM
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DEVELOPMENT OF A MORPHOMETRIC MAGNETIC RESONANCE IMAGE PARAMETER SUITABLE FOR DISTINGUISHING BETWEEN NORMAL DOGS AND DOGS WITH CEREBELLAR ATROPHY
Neurodegenerative diseases affect the cerebellum of numerous dog breeds.

Although subjective, magnetic resonance (MR) imaging has been used to detect cerebellar atrophy in these diseases, but there are few data available on the normal size range of the...

Veterinary Radiology and Ultrasound:  Feb 16 2010 9:03PM
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Automatic cerebral and cerebellar hemisphere segmentation in 3D MRI: adaptive disconnection algorithm
Zhao l et al.

the authors also applied the adaptive disconnection method to clinical images of 22 healthy controls and 18 patients with schizophrenia.

Automatic cerebral and cerebellar hemisphere segmentation in 3D MRI: adaptive disconnection...

MDLinx:  Feb 12 2010 10:22AM
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