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Autosomal dominant multiple syringomas linked to chromosome 16q22
Background The condition of multiple syringomas is a common skin problem that begins in early adulthood and is characterized by the appearance of skin-coloured papules around the eyes.

Previous reports have demonstrated that some cases of multiple syringomas...

British Journal of Dermatology: Mar 11 2010 10:32AM

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Polymorphisms in human histamine receptor H4 gene are associated with atopic dermatitis
Background Atopic dermatitis (AD) is a chronic skin disease affecting more than 15% of children and 2% of adults.

A strong connection between genetic factors and AD has been described for a long time.

Histamine receptor H4 (HRH4) has been shown to be...

British Journal of Dermatology: Mar 1 2010 7:10PM

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Noninvasive bioengineering assessment of the skin barrier function in patients with chronic venous insufficiency
Background Chronic venous insufficiency (CVI) comprises all symptoms caused by permanent venous and capillary hypertension.

While the clinical manifestations of the disease have been well characterized, there is little knowledge on the skin barrier function...

British Journal of Dermatology: Mar 1 2010 7:10PM

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Differential gene expression in drug hypersensitivity reactions: induction of alarmins in severe bullous diseases
Background Delayed hypersensitivity reactions to drugs can be life-threatening and constitute a growing problem in clinical practice.

Although drug-specific T cells seem to be involved, the cellular and molecular bases of their aetiopathology are not fully...

British Journal of Dermatology: Feb 26 2010 9:29AM

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Interactions between ultraviolet light exposure and DNA repair gene polymorphisms may increase melanoma risk
_ Interactions between ultraviolet light exposure and DNA repair gene polymorphisms may increase melanoma risk.

British Journal of Dermatology: Feb 26 2010 9:29AM

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