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Researchers Illuminate Mechanisms that Regulate DNA Damage Control, Replication
Since Ddk is often deregulated in human cancers, this new understanding of its role in DNA damage control could help shape new cancer therapies.The research was published in the December 24 issue of Molecular Cell. Accurate DNA...
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Researchers Illuminate Mechanisms that Regulate DNA Damage Control, Replication
Source: Burnham Institute for Medical Research Libraries Science News Keywords DNA, DDK, CANCER, REPLICATION Contact Information Available for logged-in reporters only Description Scientists at Burnham Institute for Medical Research have...
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Mechanisms That Regulate DNA Damage Control And Replication Illuminated
ScienceDaily (Jan.5, 2009) Scientists at Burnham Institute for Medical Research (Burnham) have demonstrated important new roles for the protein kinase complex Cdc7/Dbf4 or Cdc7/Drf1 (Ddk) in monitoring damage control during DNA...
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Researchers Illuminate Complex Mechanisms That Regulate DNA Damage Control
47 CST Scientists at Institute for Medical Research have demonstrated important new roles for the protein kinase complex Cdc7/Dbf4 or Cdc7/Drf1 (Ddk) in monitoring damage control during DNA replication and reinitiating replication following...
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Improved Understanding Of Complex Mechanisms That Regulate DNA Damage Control And Replication In The Cell Cycl
Scientists at Burnham Institute for Medical Research (Burnham) have demonstrated important new roles for the protein kinase complex Cdc7/Dbf4 or Cdc7/Drf1 (Ddk) in monitoring damage control during DNA replication and reinitiating replication...
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Mechanisms of kidney fibrosis and the role of antifibrotic therapies
Deelman L et al.- Podocytes are recognized to play a key role in the development of kidney fibrosis. New antifibrotic therapies are rapidly progressing toward definitive clinical trials but will need to be tested on top of the existing...
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A New Light On The Anti-tumor Mechanisms Of Scutellaria Barbata
GastroIntestinal / Gastroenterology News Main Category: GastroIntestinal / Gastroenterology Also Included In: Cancer / Oncology email to a friend printer friendly view / write opinions rate article Current Article Ratings: Patient / Public:...
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Journal of the American Academy of Child & Adolescent Psychiatry January 2009 Table of Contents
Newswise Journal of the American Academy of Child & Adolescent Psychiatry Volume 18 Number 1 January 2009 HERE AND THERE In This Issue/Abstract Thinking: Thinking Inside the Box, Stacy Drury EDITORIAL Childhood Psychopathology Can Be...
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Ischemia/Reperfusion Injury in Kidney Transplantation: Mechanisms and Prevention
Kosieradzki M et al.- Kidneys from such donors are exposed to much greater ischemic damage before recovery and show reduced chances for proper early as well as long-term function. Storage of kidneys, especially those recovered from ECD ...
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Expression of hemoglobin in rodent neurons
Hemoglobin is the major protein in red blood cells and transports oxygen from the lungs to oxygen-demanding tissues, like the brain.Mechanisms that facilitate the uptake of oxygen in the vertebrate brain are unknown. In...
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Mechanisms involved in the down-regulation of TCR [zeta] chain in tumor versus peripheral blood of oral cancer
In peripheral blood, the decrease in TCR chain is inversely correlated with the tumor stage TCR chain degradation in the peripheral blood involves ubiquitination and subsequent targeting for degradation in the lysosome Decreased expression...
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Yeast Mimics Severity Of Mutations Leading To Fatal Childhood Illness
Scientists report that human gene mutations expressed in yeast cells can predict the severity of Batten Disease, a fatal nervous system disorder that begins during childhood.The new study published in Disease Models & Mechanisms...
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Nicotinic Acid: Pharmacological Effects and Mechanisms of Action
Gille A et al.- Pharmacological doses of nicotinic acid induce a profound change in the plasma levels of various lipids and lipoproteins. The ability of nicotinic acid to strongly increase the plasma concentration of high-density...
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New Research Lights Up Chronic Bacterial Infection Inside Bone
A new report demonstrates how a sensitive imaging technique gives scientists the upper hand in seeking out bacteria in chronic infections.Listeria monocytogenes is a type of pathogenic bacteria that can cause severe illness and death.
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Mutations Common To Cancer And Developmental Disorder Examined In A Novel Disease Model
New research sheds light on a common link between tumor formation and Costello Syndrome, an inherited developmental disorder in which patients have cardiac defects, mild mental retardation, and face-shape abnormalities.The study published...
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Scientist Targeting Mechanisms and Treatment of Neurodegenerative Disorders Receives Endowed Chair a
Town's research focuses on molecular genetics, cellular and molecular biology, and pathology and imaging.His work has shown that key immune molecules play central roles in neurodegenerative disorders such as Alzheimer's disease,...
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[Review Articles] Metabotropic Glutamate 1 Receptor: Current Concepts and Perspectives
Department of Pharmacology, Innsbruck Medical University, Innsbruck, Austria (F.F., L.C.); Department of Human Physiology and Pharmacology, University 'La Sapienza,' Rome, Italy (F.N.); and I.Neuromed, Pozzilli, Italy (F.N.) I.
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Mechanisms Accounting for Fluoroquinolone Resistance in Escherichia coli Clinical Isolates
Fluoroquinolone MICs are increased through the acquisition of chromosomal mutations in the genes encoding gyrase (gyrA and gyrB) and topoisomerase IV (parC and parE), increased levels of the multidrug efflux pump AcrAB, and the plasmid-borne...
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Traumatic Brain Injury The Focus Of Special Issue Of Archives Of Physical Medicine And Rehabilitation
News Archive [link] Web Wikipedia Medical Dictionary [link] login | register Neurology / Neuroscience News Main Category: Neurology / Neuroscience Also Included In: Rehabilitation / Physical Therapy; Veterans / Ex-Servicemen email to a...
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Absorption Measurements of Cell Monolayers Relevant to Mechanisms of Laser Phototherapy: Reduction or Oxidatio
Karu TI et al.- The experimental results of the work demonstrate that irradiation at 632.8 nm causes either a relative reduction of the photoacceptor, putatively cytochrome c oxidase, or its relative oxidation, depending on the initial...
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Researchers Advance Knowledge Of Little 'nano-machines' In Our Body
A discovery by Canada-U.S.biophysicists will improve the understanding of ion channels, akin to little nano-machines or 'nano-valves' in our body, which when they malfunction can cause genetic illnesses that attack muscles, the central...
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Little 'Nano-Machines' In Our Bodies
A discovery by Canada-U.S.biophysicists will improve the understanding of ion channels, akin to little 'nano-machines' or 'nano-valves' in our body, which when they malfunction can cause genetic illnesses that attack muscles, the central...
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Distinct Neurophysiological Mechanisms Mediate Mixing Costs and Switch Costs
_ Distinct Neurophysiological Mechanisms Mediate Mixing Costs and Switch Costs.
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Human gene mutations expressed in yeast may predict severity of fatal childhood illness
Researchers at the University College London say that it is possible to predict the severity of Batten Disease, a fatal nervous system disorder that begins during childhood, by expressing human gene mutations in yeast cells.The...
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Yeast mimics severity of mutations leading to fatal childhood illness
Scientists express human gene mutations in yeast in order to study Batten disease, a fatal childhood neurodegenerative disorder December 22, 2008, Cambridge, UK Scientists report that human gene mutations expressed in yeast cells can predict...
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