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Diabetic Retinopathy, But Not Nephropathy, Benefits from Renin-Angiotensin Blockade
In type 1 diabetes, blockade of the renin-angiotensin system to prevent nephropathy 'is not supported,' a New England Journal of Medicine study finds.Study investigators randomized some 300 patients with type 1 diabetes to daily therapy...
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Genetic polymorphisms of paraoxonase-1 are associated with chronic kidney disease in Japanese women
1Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Yamagata, Japan 2HuBit Genomix Research Institute, Tokyo, Japan 3First Department of Internal Medicine, Fukushima Medical University, Fukushima,...
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The link between obesity and albuminuria: adiponectin and podocyte dysfunction
1Center for Renal Translational Medicine, University of California, San Diego, La Jolla, CA/Veterans Administration San Diego Health Care System, La Jolla, California, USA Correspondence: Kumar Sharma, Center for Renal Translational Medicine...
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Nephrotic Syndrome in Diabetic Kidney Disease: An Evaluation and Update of the Definition
(Click the title below to leave the MDLinx Network and go to the Journal's Website) American Journal of Kidney Diseases, 06/29/09 Print Save in My Library Free Abstract Stoycheff N et al.- The historical definition of nephrotic-range...
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Albuminuria Strongly Associated with Stroke Risk
SEATTLE-Albuminuria is the renal biomarker most strongly associated with risk of incident stroke, researchers reported here at the AAN annual meeting.The findings raise the possibility that medication to reduce albuminuria in...
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Effects of Atorvastatin on Kidney Outcomes and Cardiovascular Disease in Patients With Diabetes: An Analysis F
Save in My Library Free Abstract Colhoun HM et al.- A modest beneficial effect of atorvastatin on eGFR, particularly in those with albuminuria, was observed. Atorvastatin did not influence albuminuria incidence.
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FibroGen Begins Enrollment of Phase 2 Study of FG-3019, Monoclonal Antibody Against CTGF, in Patients with Dia
This phase 2 trial is a randomized, double-blind, placebo-controlled study that will test two dose levels of FG-3019 and is expected to enroll 150 patients with diabetic kidney disease (DKD) across multiple centers.FG-3019 will be...
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The Selective Vitamin D Receptor Activator for Albuminuria Lowering (VITAL) Study: Study Design and Baseline C
Today in Radiology/Diagnostics...The Selective Vitamin D Receptor Activator for Albuminuria Lowering (VITAL) Study: Study Design and Baseline C.
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FibroGen Begins Enrollment of Phase 2 Study of FG-3019, Monoclonal Antibody Against CTGF, in Patients with Dia
- FibroGen, Inc.today announced that enrollment has commenced in a phase 2 clinical trial designed to evaluate the efficacy and safety of FG-3019, a fully human monoclonal antibody against connective tissue growth factor (CTGF), in...
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FibroGen Begins Enrollment of Phase 2 Study of FG-3019, Monoclonal Antibody Against CTGF, in Patients with Dia
FibroGen, Inc.today announced that enrollment has commenced in a phase 2 clinical trial designed to evaluate the efficacy and safety of FG-3019, a fully human monoclonal antibody against connective tissue growth factor (CTGF), in patients...
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Prediction of albuminuria by different blood pressure measurement methods in type 1 diabetes: a pilot study
1Third University Department of Medicine, Hypertension Center, Sotiria Hospital, Athens, Greece 2Depatrment of Biochemistry, P&A Kyriakou Children's Hospital, Athens, Greece 3Department of Nephrology, P&A Kyriakou Children's...
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Obesity Is Associated With Albuminuria in Diabetic Adults
_ Obesity Is Associated With Albuminuria in Diabetic Adults.
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Obesity Is Associated With Albuminuria in Diabetic Adults
_ Obesity Is Associated With Albuminuria in Diabetic Adults.
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Fenofibrate use linked with fewer amputations in type 2 diabetes
Use of fenofibrate can lower the risk of some types of amputation in people with type 2 diabetes, according to a prespecified subanalysis of a 9,795-patient study, published recently in The Lancet (2009;373:1780).The analysis showed that,...
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Microalbuminuria linked to venous thromboembolism
NEW YORK (Reuters Health) - Microalbuminuria, which is known to be associated with arterial thromboembolism, is also independently linked to an elevated risk of venous thromboembolism (VTE), according to a report in the Journal of the...
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Pharmalink AB Completes Phase II Clinical Study With Renal Disease Drug Nefecon
- Results to be Presented at World Congress of Nephrology 2009 STOCKHOLM, Sweden, April 29, 2009 /PRNewswire/ --Pharmalink AB announced today that it has completed its open Phase II trial evaluating the efficacy and safety of Nefecon(R) in...
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GFR and albumin testing predict progression to renal failure
NEW YORK (Reuters Health) - Assessing kidney function with both the estimated glomerular filtration rate (eGFR) and with urinary albumin levels can help predict whether chronic kidney disease will progress to end-stage renal disease (ESRD),...
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