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  Current Search:  amphotericin: 14, b: 3665     

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Pharma manufacturing news in brief
Our round-up of news in the pharmaceutical manufacturing arena covers developments at Genzyme, Enzon/Sigma-Tau, Catalent, Synco Bio Partners, Angel Biotech, Pfizer/Peakdale Molecular and Gorbec Pharmaceutical Services.

Genzyme has appointed a new president of...

Pharmafocus:  Feb 8 2010 10:32AM
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Hospital deaths
Health correspondent, BBC Midlands Today Six patients have died at a West Midlands hospital trust following serious errors with medication since 2006, the BBC can reveal.

Four deaths, at Heartlands Hospital in Birmingham, have already been made public.

BBC:  Jan 26 2010 12:09PM
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Hospital drugs deaths total six
by Michele Paduano Health correspondent, BBC Midlands Today Rosemary McFarlane died after a routine hospital procedure Six patients have died at a West Midlands hospital trust following serious errors with medication since 2006, the BBC can reveal.

Four...

BBC:  Jan 26 2010 11:48AM
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Murine Model of a Disseminated Infection by the Novel Fungus Fonsecaea monophora and Successful Treatment with
We have evaluated the efficacy of posaconazole, amphotericin B, and itraconazole in a murine model of disseminated infection by Fonsecaea monophora.

Of these three antifungal drugs tested, posaconazole prolonged survival significantly and reduced...

AAC:  Jan 23 2010 6:37AM
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Apoptosis in Candida biofilms exposed to amphotericin B
Rawya S.

AlDhaheri et al.

The results demonstrate an apoptotic process in amphotericintreated biofilms of three Candida species.

Apoptosis in Candida biofilms exposed to amphotericin B.

MDLinx:  Jan 21 2010 11:12AM
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Treatment of HIV-Related Inflammatory Cerebral Cryptococcoma with Adalimumab - brief report
50:e7-e10 Amy M.

Sitapati,1 Cynthia L.

Kao,1 Edward R.

Cachay,1 Homeyra Masoumi,2 Robert S.

Wallis,3 and W.

Christopher Mathews1; for the Owen Clinic Study Group Departments of 1Medicine and 2Pathology, University of California, San Diego School of...

National AIDS Treatment Advocacy Project:  Jan 19 2010 8:20AM
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Nurses who overdosed two Heartlands Hospital cancer patients escape
NURSES involved in two cancer patients dying from a toxic drug overdose at a Birmingham hospital will not be disciplined by their professional body because they are sorry.

Vongai Gondo and Catherine Kunatsa wrongly made up the prescriptions that led to...

Birmingham Evening Mail:  Jan 18 2010 3:32PM
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Nurses who overdosed two Heartlands Hospital cancer patients escape punishment by professional body
NURSES involved in two cancer patients dying from a toxic drug overdose at a Birmingham hospital will not be disciplined by their professional body because they are sorry.

Vongai Gondo and Catherine Kunatsa wrongly made up the prescriptions that led to...

Birmingham Evening Mail:  Jan 18 2010 12:19PM
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Researchers Suggest Adjusting Doses of Antibiotics According to Bodyweight
-- Doses of antibiotics and other antimicrobial agents should take into account the patient's bodyweight, to maximise their potential effectiveness.

The issues are discussed in a viewpoint in this week's edition of The Lancet.

'For most widely used...

Doctors Guide:  Jan 15 2010 7:26AM
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Amphotericin B Therapy in Children with Visceral Leishmaniasis: Daily vs. Alternate Day, a Randomized Trial
Singh UK et al.

The duration of stay and cost of therapy was significantly lower in Group A children who left the hospital against medical advice, which was also significantly more in Group B.

Amphotericin B Therapy in Children with...

MDLinx:  Jan 14 2010 11:17AM
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Feasibility, tolerability, and outcomes of nebulized liposomal amphotericin B for Aspergillus infection prevention in lung transplantation - Corrected Proof
Background: Nebulized amphotericin B deoxycholate (n-ABD) is used to prevent Aspergillus infection in lung transplantation.

Nebulized liposomal amphotericin B (n-LAB) is another option; however, no clinical data are available on the...

Journal of Heart and Lung Transplantation:  Jan 11 2010 7:46PM
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Findings from United Arab Emirates University in liposomes reported
- (NewsRx.com) According to recent research from Al Ain, United Arab Emirates, 'A high intermittent dose regimen (group A: 10 mg kg(-1) on day 1, 5 mg kg(-1) on days 3 and 6) was compared with standard dosing (group B: 3 mg kg(-1) per day for 14 days) of...
Pharmacy Choice:  Jan 7 2010 7:54PM
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Infections After Bone Marrow Transplantation Using Cyclosporine
Kay HEM et al.

Fungal infections were prevented by nystatin and amphotericin thus avoiding the difficult combination of cyclosporine and ketaconazole.

Infections After Bone Marrow Transplantation Using Cyclosporine.

MDLinx:  Jan 5 2010 10:28AM
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Early ART in the Setting of Acute OIs
Major trials support this approach, but the strategy is not without risk.

When the results of ACTG A5164 came out first at CROI 2008 and then in published form this summer (JW AIDS Clin Care Jun 22 2009) we thought we could finally answer the question of when...

AIDS Clinical Care:  Jan 4 2010 11:17PM
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